Tocolysis and Neurodevelopment of Children Born Very Preterm.

Importance: Neurodevelopmental outcomes of very preterm children exposed to tocolytics are not well described.

Objective: To investigate whether tocolysis administered after spontaneous preterm labor is associated with neurodevelopmental outcomes at 5.5 years and to assess whether the type of tocolytic drug is associated with neurodevelopmental outcomes among infants exposed.

Effects of MgSO Alone or Associated with 4-PBA on Behavior and White Matter Integrity in a Mouse Model of Cerebral Palsy: A Sex- and Time-Dependent Study.

Cerebral palsy (CP) is defined as permanent disorders of movement and posture. Prematurity and hypoxia-ischemia (HI) are risk factors of CP, and boys display a greater vulnerability to develop CP. Magnesium sulfate (MgSO) is administered to mothers at risk of preterm delivery as a neuroprotective agent.