Publications by authors named "Thiago Sousa"

Objective: This study aimed to investigate the effects of power training (PT) using elastic bands combined with endurance training (ET) on pulse pressure (PP), systolic (SBP) and diastolic blood pressures (DBP), autonomic response (AR), and functional parameters in older adults.

Methods: Thirty participants were randomly assigned to the control group ( n = 15) and the intervention group (IG) ( n = 15). IG participants performed PT with elastic bands combined with ET twice weekly for 8 weeks.

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Statement Of Problem: With advancements in digital technologies, the digital workflow has revolutionized the fabrication of occlusal devices through additive methods using 3-dimensional (3D) printing. However, an established protocol for polishing 3D printed occlusal devices is lacking, despite this step being crucial for minimizing surface porosity, material fatigue and preventing bacterial plaque accumulation, thereby contributing to device longevity.

Purpose: The purpose of this in vitro study was to evaluate the impact of polishing systems on the surface roughness and Vickers microhardness of heat-polymerizing acrylic resin and 3D printing resins used for occlusal devices.

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Bacterial wilt, caused by , is one of the main challenges for sustainable tomato production in the Amazon region. This study evaluated the potential of bacteria isolated from sediments of the Solimões and Negro rivers for the biocontrol of this disease. From 36 bacteria selected through in vitro antibiosis, three promising isolates were identified: RN 11, sp.

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), etiological agent for the coronavirus disease 2019 (COVID-19), has resulted in over 775 million global infections. Early diagnosis remains pivotal for effective epidemiological surveillance despite the availability of vaccines. Antigen-based assays are advantageous for early COVID-19 detection due to their simplicity, cost-effectiveness, and suitability for point-of-care testing (PoCT).

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Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation.

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Previous studies have investigated the effects of different combined training programs involving traditional resistance training and aerobic exercise on hemodynamic parameters and arterial stiffness in older adults. However, little is known about the impact of power training combined with endurance training on these variables in hypertensive older adults. Therefore, this study aimed to investigate the effects of dynamic power training with elastic bands combined with endurance training on arterial stiffness and hemodynamic parameters in hypertensive older adults.

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The conducted investigation encompassed the comprehensive integration of mechanical, environmental, chemical, and microstructural evaluations of a composite amalgamating sandy soil and a synthetic polymer at two distinct concentrations (2.5% and 5%) across multiple curing intervals (0, 1, 2, 4, 7, 15, 30, and 45 days). The studied soil originates from an environmentally significant protected area in Brazil.

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Background: Probiotics have gained attention for their potential maintaining gut and immune homeostasis. They have been found to confer protection against pathogen colonization, possess immunomodulatory effects, enhance gut barrier functionality, and mitigate inflammation. However, a thorough understanding of the unique mechanisms of effects triggered by individual strains is necessary to optimize their therapeutic efficacy.

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The genus Trichoderma comprises more than 500 valid species and is commonly used in agriculture for the control of plant diseases. In the present study, a Trichoderma species isolated from Scleronema micranthum (Malvaceae) has been extensively characterized and the morphological and phylogenetic data support the proposition of a new fungal species herein named Trichoderma agriamazonicum. This species inhibited the mycelial growth of all the nine phytopathogens tested both by mycoparasitism and by the production of VOCs, with a highlight for the inhibition of Corynespora cassiicola and Colletotrichum spp.

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High exposure to sedentary behavior and lower levels of physical activity can lead to excess body weight (EBW). The aim of this study was to estimate the prevalence of EBW and the direct association under the condition of sociodemographic, university, and behavioral moderating characteristics, between physical activity and sitting time related to EBW in Brazilian university students. A cross-sectional study was carried out with 1,110 university students from a federal public institution in Minas Gerais, Brazil.

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Biofilms are complex microecosystems with valuable ecological roles that can shelter a variety of microorganisms. Spirochetes from the genus Leptospira have been observed to form biofilms in vitro, in rural environments, and in the kidneys of reservoir rats. The genus Leptospira is composed of pathogenic and non-pathogenic species, and the description of new species is ongoing due to the advent of whole genome sequencing.

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Influenza A virus (IAV) infection affects the human respiratory tract, causing an acute and highly contagious disease. Individuals with comorbidities and in the extremes of age are classified as risk groups for serious clinical outcomes. However, part of the severe infections and fatalities are observed among young healthy individuals.

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Prosthesis discomfort and a lack of skin-like quality is a source of patient dissatisfaction with facial prostheses. To engineer skin-like replacements, knowledge of the differences between facial skin properties and those for prosthetic materials is essential. This project measured six viscoelastic properties (percent laxity, stiffness, elastic deformation, creep, absorbed energy, and percent elasticity) at six facial locations with a suction device in a human adult population equally stratified for age, sex, and race.

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Mercury is a non-essential and toxic metal that induces toxicity in most organisms, but endophytic fungi can develop survival strategies to tolerate and respond to metal contaminants and other environmental stressors. The present study demonstrated the potential of mercury-resistant endophytic fungi in phytoremediation. We examined the functional traits involved in plant growth promotion, phytotoxicity mitigation, and mercury phytoremediation in seven fungi strains.

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Article Synopsis
  • Trichoderma is a fungi known for producing nonribosomal peptides called peptaibols, which have strong antimicrobial and anticancer properties, and can help plants resist pathogens.
  • Researchers analyzed peptaibols from a newly identified marine strain of Trichoderma using advanced mass spectrometry, identifying it as a unique species not previously seen in marine environments.
  • The study highlighted the discovery of various biosynthetic gene clusters related to these peptides, leading to the identification of two new series of peptaibols called "endophytins," showcasing the effective use of genome mining and mass spectrometry in natural product research.
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Objective: To assess the influence of the COVID-19 pandemic on hospital admissions (HA), intra-hospital deaths (HD), and intra-hospital lethality rates (HL) related to respiratory diseases (RD) other than COVID-19 in Brazil.

Methods: This observational time-series study was conducted through comparative analyses of the HA, HD, and HL related to non-COVID-19 RD registered between March and December 2020 by the Brazilian Unified Public Health System on the DataSUS Tabnet platform, using as reference the values recorded in the same period of 2019 and those projected by linear regression methods for 2020, considering the period from 2015 to 2019. The adopted statistical significance level was 5% (p < 0.

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Fungi of the genus Penicillium section Sclerotiora have as their main characteristic the presence of orange-pigmented mycelium, which is associated with sclerotiorin, a chlorinated secondary metabolite of the azaphilone subclass of polyketides. Sclerotiorin presents anti-diabetes, antioxidant, anti-inflammatory, anti-Alzheimer, antiviral, and antimicrobial activities, which has always attracted the attention of researchers worldwide. During our ongoing search for azaphilone-producing Amazonian fungi, the strain of Penicillium MMSRG-058 was isolated as an endophyte from the roots of Duguetia stelechantha and showed great capacity for producing sclerotiorin-like metabolites.

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In Brazil, Salmonella enterica serovar Enteritidis is a significant health threat. Salmonella enterica serovar Enteritidis SE3 was isolated from soil at the Subaé River in Santo Amaro, Brazil, a region contaminated with heavy metals and organic waste. Illumina HiSeq and Oxford Nanopore Technologies MinION sequencing were used for de novo hybrid assembly of the Salmonella SE3 genome.

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Some chronic respiratory diseases can cause hypoxemia and, in such cases, long-term home oxygen therapy (LTOT) is indicated as a treatment option primarily to improve patient quality of life and life expectancy. Home oxygen has been used for more than 70 years, and support for LTOT is based on two studies from the 1980s that demonstrated that oxygen use improves survival in patients with COPD. There is evidence that LTOT has other beneficial effects such as improved cognitive function, improved exercise capacity, and reduced hospitalizations.

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Article Synopsis
  • Probiotics are microorganisms that promote health, especially by modulating immune responses and reducing inflammation.
  • This study focused on nine strains of a specific probiotic bacteria, analyzing their genetic makeup to identify genes that contribute to their health benefits for humans.
  • Key findings included shared genes linked to stress response, adhesion to human proteins, and the production of beneficial compounds, highlighting the potential of these strains to support gut health and overall wellness.
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Biochemical, serological, and molecular methods have been developed for the laboratory diagnosis of diseases caused by (CP), but the identification of the pathogen and biovars differentiation may be time-consuming, expensive, and confusing compared with other bacteria. This study aimed to evaluate MALDI Biotyper and Overall Genome Relatedness Index (OGRI) analysis to optimize the identification and differentiation of biovars of . Out of 230 strains isolated from several hosts and countries, 202 (87.

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Objective: Assess the prevalence of self-reported TMD symptoms and anxiety and check the quality of sleep and life during the distance learning period in university students at the University of Brasilia (UnB).

Materials And Methods: The participants were students from the Health Sciences College and Medicine College at UnB. Self-administered questionnaires were used to evaluate symptoms of TMD, quality of life, and sleep quality.

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Article Synopsis
  • - The influenza A virus (IAV) poses a significant public health risk, causing yearly outbreaks and has the potential for pandemics, with neuraminidase inhibitors (NAIs) being the primary treatment but new drugs like baloxavir marboxil (BXM) are emerging.
  • - A study evaluated the antiviral resistance of Brazilian IAV strains from 2017 to 2019, identifying specific mutations associated with reduced drug effectiveness, but finding generally low resistance levels in analyzed strains.
  • - Results showed that the majority of Brazilian IAV isolates maintain a normal susceptibility to the most common NAI, oseltamivir (OST), and highlighted the importance of ongoing surveillance for resistance.
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Salmonella Typhimurium is associated with foodborne diseases worldwide, including in Peru, and its emerging antibiotic resistance (AMR) is now a global public health problem. Therefore, country-specific monitoring of the AMR emergence is vital to control this pathogen, and in these aspects, whole genome sequence (WGS)—based approaches are better than gene-based analyses. Here, we performed the antimicrobial susceptibility test for ten widely used antibiotics and WGS-based various analyses of 90 S.

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Zika virus (ZIKV) is a mosquito-borne virus that is phylogenetically close to other medically important flaviviruses with high global public health significance, such as dengue (DENV) and yellow fever (YFV) viruses. Correct diagnosis of a flavivirus infection can be challenging, particularly in world regions where more than one flavivirus co-circulates and YFV vaccination is mandatory. Acid nucleic aptamers are oligonucleotides that bind to a specific target molecule with high affinity and specificity.

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