Early Changes in Eating Behavior Patterns and Their Relationship with Weight Outcomes in Patients Undergoing Bariatric Surgery.

Background/objective: Eating behaviors (EB) correlate with weight loss after bariatric surgery (BS). Therefore, the investigation of EB could guide interventions to prevent insufficient weight outcomes.

Method: A prospective cohort of 85 patients undergoing Roux-en-Y Gastric Bypass (RYGB; 84.

Case Report: Abdominal Wall Reconstruction in a High-Risk Patient With Incisional Hernia and Complications From Oncological Treatment.

A high risk patient with evisceration underwent to abdominal wall reconstruction without mesh or drains. We present a case of a 62 years-old female patient with a significant medical history of Wilson's disease-related hepatopathy Child-Pugh class B classification, sequelae of a stroke, and relevant surgical background including total hysterectomy, oophorectomy, and Hartmann's procedure for ovarian neoplasm stage 3. The patient developed a large incisional hernia in the midline incision while undergoing Bevacizumab (Avastin) treatment for clinical oncology.

Discovery of indolizine lactones as anticancer agents and their optimization through late-stage functionalization.

Indolizines fused with a seven-member lactone ring were identified as a promising scaffold in the search for new anticancer agents. Through a modular synthetic sequence, a library of and indolizines lactones had their antiproliferative activity evaluated against hormone-refractory prostate DU-145 and triple-negative breast MDA-MB-231 cancer cell lines. A methoxylated analogue was identified as an initial hit against MDA-MB-231 and late-stage functionalization of the indolizine core led to analogues within potencies up to twenty times higher than the parent precursor.

Effect of pulmonary rehabilitation on functional capacity in individuals treated for pulmonary tuberculosis: a systematic review protocol.

Objective: The aim of this review is to synthesize the available evidence on the effectiveness of pulmonary rehabilitation on the functional capacity of people who have finished drug treatment for pulmonary tuberculosis.

Introduction: Pulmonary rehabilitation is a treatment option for physical functional problems that persist after pharmacological treatment for tuberculosis; however, the results of primary studies on the subject are inconclusive.

Inclusion Criteria: This review will consider for inclusion studies carried out with adults (≥18 years old) who have completed pharmacological treatment for tuberculosis.

Brueckner Doubles variation of W1 theory (W1BD) adapted to pseudopotential: W1BDCEP theory.

Composite methods are the combination of ab initio calculations used to achieve high precision in the face of a computational reduction. Weizmann-n theories (n = 1, 2, 3, and 4) stand out for presenting a high precision, and a version of the W1 theory is the W1BD theory that uses ab initio Brueckner Doubles (BD) methods. One way to reduce the computational cost of composite methods and maintain accuracy is to use pseudopotentials in the calculation steps; in this context, W1BDCEP composite method was developed from the respective W1BD all-electron version by considering the implementation of compact effective pseudopotential (CEP).

A framework for near-real time monitoring of diversity patterns based on indirect remote sensing, with an application in the Brazilian Atlantic rainforest.

Monitoring biodiversity change is key to effective conservation policy. While it is difficult to establish biodiversity monitoring programs at broad geographical scales, remote sensing advances allow for near-real time Earth observations that may help with this goal. We combine periodical and freely available remote sensing information describing temperature and precipitation with curated biological information from several groups of animals and plants in the Brazilian Atlantic rainforest to design an indirect remote sensing framework that monitors potential loss and gain of biodiversity in near-real time.

Methodologies for the synthesis of quaternary carbon centers via hydroalkylation of unactivated olefins: twenty years of advances.

Olefin double-bond functionalization has been established as an excellent strategy for the construction of elaborate molecules. In particular, the hydroalkylation of olefins represents a straightforward strategy for the synthesis of new C(sp)-C(sp) bonds, with concomitant formation of challenging quaternary carbon centers. In the last 20 years, numerous hydroalkylation methodologies have emerged that have explored the diverse reactivity patterns of the olefin double bond.

Socio-economic and environmental factors associated with the occurrence of canine infection by Leishmania infantum in Teresina, Brazil.

American visceral leishmaniasis (AVL) is a zoonosis caused by protozoan parasites of the genus Leishmania. In Brazil, the disease is caused by Leishmania infantum and the main vector is the phlebotomine sandfly Lutzomyia longipalpis, found both in natural ecotopes and in the rural and urban environments, being very well adapted to the peridomestic environment. The domestic dog has been incriminated as the main reservoir of the parasite in the urban environment, but the control measures based on culling seropositive dogs have not shown to be effective to contain the spread of the disease throughout the country.

Brønsted-acid-catalyzed selective Friedel-Crafts monoalkylation of isatins with indolizines in water.

The controlled mono-addition of indolizines to isatins under very mild conditions is described. The reaction occurs in water using diphenylphosphate as the catalyst, which is dramatically accelerated by surfactant addition. 3-Hydroxy-3-indolizinyl-2-oxindole scaffolds were synthesized in up to >99% yield.

[Effects of physical exercise on cardiovascular risk and quality of life in hypertensive elderly people].

The scope of this article is to evaluate the effects of a mixed protocol of physical exercises on cardiovascular risk (CVR), quality of life and the presence of depressive symptoms in elderly hypertensive patients. It involved a longitudinal, prospective and quasi-experimental study with 48 elderly individuals. A physical exercise protocol was developed for 16 weeks according to American College of Sports Medicine, and anthropometric variables (weight, height, body mass index and waist circumference), as well as biochemical variables (total cholesterol, LDL-c, HDL-c; triglycerides) were evaluated.

Catalyst-Free Conjugate Addition of Indolizines to -Generated Oxidized Morita-Baylis-Hillman Adducts.

Sequential one-pot 2-iodoxybenzoic acid (IBX) oxidation of Morita-Baylis-Hillman (MBH) adducts followed by catalyst-free indolizine conjugate addition was developed. The wide scopes of MBH adducts and indolizines were investigated, and densely functionalized adducts were obtained in yields of up to 94%. The conjugate addition step occurred in less than a minute at room temperature with total regioselectivity toward indolizine C3 carbon.

Acute Effects of T'ai Chi Chuan Exercise on Blood Pressure and Heart Rate in Peripheral Artery Disease Patients.

Objective: To investigate the acute effect of a t'ai chi chuan session on blood pressure and heart rate in patients with peripheral artery disease (PAD).

Design: Randomized crossover intervention study.

Setting: Outpatient therapy center.

Responses of aquatic macrophyte cover and productivity to flooding variability on the Amazon floodplain.

Macrophyte net primary productivity (NPP) is a significant but understudied component of the carbon budget in large Amazonian floodplains. Annual NPP is determined by the interaction between stem elongation (vertical growth) and plant cover changes (horizontal expansion), each affected differently by flood duration and amplitude. Therefore, hydrological changes as predicted for the Amazon basin could result in significant changes in annual macrophyte NPP.

Progressive deconstruction: a novel aneurysm treatment using the pipeline embolization device for competitive flow diversion: case report.

Background And Importance: A variety of deconstructive and reconstructive therapies have been used to treat intracranial aneurysms. The Pipeline embolization device (PED) has become a quite successful option to treat aneurysms, while reconstructing and remodeling the parent vessel. We report a case of off-label PED use, where a flow diverter was placed across the parent vessel of a giant intracranial aneurysm in a novel deconstructive strategy.

Remote sensing of aquatic vegetation: theory and applications.

Aquatic vegetation is an important component of wetland and coastal ecosystems, playing a key role in the ecological functions of these environments. Surveys of macrophyte communities are commonly hindered by logistic problems, and remote sensing represents a powerful alternative, allowing comprehensive assessment and monitoring. Also, many vegetation characteristics can be estimated from reflectance measurements, such as species composition, vegetation structure, biomass, and plant physiological parameters.