Age-related episodic memory decline and the role of amyloid-β: a systematic review.

Unlabelled: Aging has been associated with the functional decline of episodic memory (EM). Unanswered questions are whether the decline of EM occurs even during healthy aging and whether this decline is related to amyloid-β (Aβ) deposition in the hippocampus.

Objective: The main purpose of this study was to investigate data on the relationship between the age-related EM decline and Aβ deposition.

Spatial contrast sensitivity: effects of reliability, test-retest repeatability and sample size using the Metropsis software.

Purpose: The goals of the study were to further assess contrast sensitivity to (1) investigate the existence of monocular vs. binocular differences; (2) observe possible differences between sample sizes; (3) investigate the effects of test-retest repeatability.

Methods: Contrast sensitivity measurements were obtained by presenting eight horizontal sine-wave gratings (ranging from 0.

Neurostimulation Combined With Cognitive Intervention in Alzheimer's Disease (NeuroAD): Study Protocol of Double-Blind, Randomized, Factorial Clinical Trial.

Despite advances in the treatment of Alzheimer's disease (AD), there is currently no prospect of a cure, and evidence shows that multifactorial interventions can benefit patients. A promising therapeutic alternative is the use of transcranial direct current stimulation (tDCS) simultaneously with cognitive intervention. The combination of these non-pharmacological techniques is apparently a safe and accessible approach.