Oral paracoccidioidomycosis in a single-center retrospective analysis from a Brazilian southeastern population.

Background: Paracoccidioidomycosis (PCM) is the most prevalent endemic systemic fungal infection in Latin America. In Brazil, it stands out as the eighth-highest cause of mortality among chronic or recurrent infections and has the highest mortality rate among systemic mycoses. Oral mucosal lesions may be the first visible physical manifestation of the disease.

Cardiorespiratory, sedative and antinociceptive effects of dexmedetomidine alone or in combination with methadone, morphine or tramadol in dogs.

Objective: To evaluate the cardiorespiratory, sedative and antinociceptive effects of dexmedetomidine alone or in combination with methadone, morphine or tramadol in dogs.

Study Design: Experimental, blinded, randomized, crossover study.

Animals: Six mixed breed dogs (two males and four females) weighing 10 ± 4 kg.