Efficacy, acceptability, and safety of muscle relaxants for adults with non-specific low back pain: systematic review and meta-analysis.

Objective: To investigate the efficacy, acceptability, and safety of muscle relaxants for low back pain.

Design: Systematic review and meta-analysis of randomised controlled trials.

Data Sources: Medline, Embase, CINAHL, CENTRAL, ClinicalTrials.

A systematic review highlights the need to improve the quality and applicability of trials of physical therapy interventions for low back pain.

Objectives: The objective of this study was to review and assess the methodological quality of randomized controlled trials that test physical therapy interventions for low back pain.

Study Design And Setting: This is a systematic review of trials of physical therapy interventions to prevent or treat low back pain (of any duration or type) in participants of any age indexed on the Physiotherapy Evidence Database (PEDro). Existing PEDro scale ratings were used to evaluate methodological quality.