Publications by authors named "Thiago D S Rosa"

Objective: This study investigated the effects of dual-task resistance training (RT) and detraining on physical function, cognitive capacity, lipid profile, renal function, oxidative stress markers, and chronic inflammation of institutionalized older adults.

Methods: The study involved 11 older adults (83.09 ± 8.

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  • - Emerging research indicates that resistance training (RT) can help improve respiratory muscle strength in patients undergoing hemodialysis (HD), although the exact reasons for these benefits are still not fully understood.
  • - A study involving 33 HD patients compared the effects of a 24-week periodized RT program against a control group, finding significant increases in respiratory function measures (like maximal inspiratory and expiratory pressures) along with improvements in handgrip strength and fat-free mass.
  • - The results revealed that as respiratory muscle strength improved, there was also a notable decrease in interdialytic weight gain (IWG) and an increase in nitric oxide levels, suggesting these factors may play a role in the beneficial effects of RT on respiratory function in
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Background: Hemodialysis (HD) per se is a risk factor for thrombosis. Considering the growing body of evidence on blood-flow restriction (BFR) exercise in HD patients, identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training model. The aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise (RE) with BFR on this molecule.

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Evidence indicates that master athletes have higher concentration of Sirtuin 1 (Sirt1), lower body fat (BF), and greater activity of the hypothalamic-pituitary-gonadal axis in comparison to untrained peers. However, no published data have demonstrated possible mediation effect of Sirt1 in the interaction of BF and testosterone in this population. Therefore, this study compared and verified possible associations between Sirt1, BF, fat mass index (FMI), testosterone, luteinizing hormone (LH), and testosterone/luteinizing hormone (T/LH) ratio in middle-aged master athletes (n = 54; 51.

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Reis, AL, Deus, LA, Neves, RVP, Corrêa, HL Reis, TL, Aguiar, LS Honorato, FS, Barbosa, JMS, Araújo, TB, Palmeira, TRC, Simões, HG, Prestes, J, Sousa, CV, Ide, BN, and Rosa, TdS. Exercise-induced transient oxidative stress is mitigated in Down syndrome: insights about redox balance and muscle strength. J Strength Cond Res 38(3): e125-e34, 2024-This study aimed to evaluate the acute effects of a session of resistance exercise (RE) performed with elastic tubes on the redox balance and inflammatory profile in individuals with Down syndrome (DS).

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Background: Scientometric analyses of specific topics in geriatrics and gerontology have grown robustly in scientific literature. However, analyses using holistic and interdisciplinary approaches are scarce in this field of research. This article aimed to demonstrate research trends and provide an overview of bibliometric information on publications related to geriatrics and gerontology.

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Klotho is an anti-aging protein with several therapeutic roles in the pathophysiology of different organs, such as the skeletal muscle and kidneys. Available evidence suggests that exercise increases Klotho levels, regardless of the condition or intervention, shedding some light on this anti-aging protein as an emergent and promising exerkine. Development of a systematic review and meta-analysis in order to verify the role of different exercise training protocols on the levels of circulating soluble Klotho (S-Klotho) protein.

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Sirt1 is an enzyme involved in several anti-aging pathways. Associations between Sirt1, age, and body fat (BF) were assessed in master sprinters (MS; n = 35; 50.25 ±5.

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  • Kidney transplant recipients face a higher risk of severe COVID-19 and long-term complications known as Long-COVID.
  • A study surveyed 780 out of 1239 eligible kidney transplant patients, finding that 27% experienced Long-COVID, with body aches being the most common symptom.
  • Among those who provided employment status, 17% did not return to work within three months, and the severity of acute illness symptoms was the only identified risk factor for Long-COVID.
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Muscle weakness is associated with negative outcomes, in addition to being related to the pathogenesis of frailty and functional disability in the older individuals. Muscle strength and functionality are considered biomarkers of aging. Progressive resistance training (PRT) is a type of training that has been the subject of studies as it presents itself as a therapeutic option to fight the reduction of muscle strength and functionality in older individuals.

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  • * Current studies show that BFR training offers similar health benefits to traditional exercise for CKD patients, such as maintaining muscle strength and good kidney function, while showing fewer adverse effects.
  • * The review highlights the need for more research on BFR exercise, discusses its potential health effects compared to regular exercise, and identifies gaps in existing studies to guide future investigations and practical applications.
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  • Aging leads to hormone imbalance, increased body fat, and lower anti-inflammatory cytokine levels, but regular physical exercise can help combat these effects, as seen in endurance-trained middle-aged athletes (EMA).
  • A study comparing EMA and untrained age-matched individuals (UAM) found that EMA had significantly lower body fat, higher testosterone, and increased interleukin 10 (IL-10) levels.
  • The results suggest that engaging in endurance training can improve hormone profiles, reduce body fat, and promote a healthier aging process by enhancing anti-inflammatory responses.
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We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (: 157; age: 66.8 ± 3.

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  • The study investigated how different genotypes of the angiotensin-converting enzyme (ACE) affect the response of chronic kidney disease patients to long-term resistance training.
  • Over 300 patients were divided into four groups based on their ACE genotype and whether they participated in resistance training or had a control regimen.
  • Results showed that the DD genotype benefited more in blood pressure control, while those with allele I saw greater gains in muscle mass, suggesting that genotyping could help tailor rehabilitation strategies in hemodialysis clinics.
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This study analyzed the kidney function and biomarkers of health in lifelong-trained sprinters and endurance runners, and compared them to untrained aged-matched and young controls. Sixty-two men (21-66 yr.) were recruited and allocated as master athletes from sprints (n=25), master athletes from endurance events (n=8), untrained middle-aged (n=14) and young controls (n=15).

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Background: Obesity and poor strength impose higher risk factor for end-stage renal disease (ESRD) patients. It is expected that the combination of both conditions might be critically associated with the inflammatory profile in this population, especially in community-dwelling elderly. So, diagnosis of dynapenic obesity and inflammation is an important tool in the management of chronic kidney disease patients at imminent risk of hospitalization.

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Aging muscle is prone to sarcopenia and its associated telomere shortening and increased oxidative stress. Telomeres are protected by a shelterin protein complex, proteins expressed in response to DNA damage. Aerobic exercise training has shown to positively modulate these proteins while aging, but the effects of resistance training are less clear.

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Background And Aim: Growth of elderly population is a worldwide phenomenon that impacts public health. The objective of this study was to compare the pain levels, strength, and quality of life among elderly obese with diabetes or hypertension.

Materials And Methods: The study cohort comprised 52 obese elderly subjects with hypertension (n = 35) and diabetes (n = 17).

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Anemia is an inherent complication of older individuals with end-stage renal disease (ESRD) that is associated with inflammation which in turn is an important factor in the activation of hepcidin that contributes to the decrease in serum iron. Athough resistance training (RT) seems to reduce inflammation in ESRD, its influence on hepcidin and iron availability in hemodialysis patients is unclear. Therefore, the aim of this study was to exemine the effects of RT in on inflammatory profile, hepcidin, and iron status in older individuals with ESRD.

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Santos, GAd, Numata-Filho, ES, Rosa, TdS, Passos Neves, RV, Simões, HG, and Moreira, SR. Anaerobic threshold determination in cycle ergometer from rating of perceived exertion. J Strength Cond Res 36(5): 1277-1281, 2022-The objective of the study was to investigate the validity of the rating of perceived exertion threshold (TRPE) for anaerobic threshold (AT) estimation during an incremental test (IT) on a cycle ergometer.

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Resistance exercise (RE) can be an excellent modality for glycemic control. Studies have demonstrated that a single RE session can reduce glycemia in subjects with or without diabetes. Little is known about the dose-response effect of RE on glycemic control.

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The aims of the present study were to compare the effects of two periodization models on metabolic syndrome risk factors in obese adolescents and verify whether the angiotensin-converting enzyme (ACE) genotype is important in establishing these effects. A total of 32 postpuberty obese adolescents were submitted to aerobic training (AT) and resistance training (RT) for 14 weeks. The subjects were divided into linear periodization (LP, n = 16) or daily undulating periodization (DUP, n = 16).

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