Sympathetic control of the coronary circulation during trigeminal nerve stimulation in humans.

Purpose: We sought to investigate the sympathetic mechanism controlling coronary circulation during trigeminal nerve stimulation in healthy women.

Methods: The protocol consisted of 3 min of trigeminal nerve stimulation (TGS) with cold stimuli to the face, in two conditions: (1) control and β-blockade (oral propranolol), and (2) control and α-blockade (oral prazosin).

Results: Thirty-one healthy young subjects (women: n = 13; men: n = 18) participated in the study.