Publications by authors named "Thiago Bittencourt Ottoni de Carvalho"
Introduction: The complexity of the nasal tip structures and the impact of surgical maneuvers make the prediction of the final outcome very difficult. Therefore, no single technique is enough to correct the several anatomical presentations, and adequate preoperative planning represents the basis of rhinoplasty.
Objective: To present results of rhinoplasty, through the gradual surgical approach to nasal tip definition based on anatomical features, and to evaluate the degree of patient satisfaction after the surgical procedure.
Article Synopsis
- Juvenile nasopharyngeal angiofibroma (JNA) is a rare vascular tumor that mostly affects young males, particularly between the ages of 14 and 25, and is linked to the GSTM1 gene.* -
- A study in Brazil examined ten male patients with JNA, finding that 40% had the GSTM1-null genotype, but there was no significant correlation between their stage of disease or age and the genotype.* -
- The results suggest a potential association between the GSTM1-null genotype and JNA in this specific Brazilian population, highlighting the need for further research in this area.*
Article Synopsis
- Serotonin affects various bodily functions, including sleep, and variations in the 5-HT2A receptor gene may increase the risk for obstructive sleep apnea syndrome (OSAS).
- This study aimed to assess the presence of specific genetic variations (102T-C and -1438G-A polymorphisms) in Brazilian patients with and without OSAS.
- Findings showed no significant difference for the 102T-C variant, but the AA genotype of the -1438G-A polymorphism was more common in OSAS patients, suggesting a potential link between this genetic variation and the condition.
Article Synopsis
- Obstructive sleep apnea syndrome (OSAS) is influenced by genetic factors, particularly the serotonin (5-HT) system, which regulates various bodily functions including sleep.
- The study aimed to analyze the prevalence of specific genetic polymorphisms (T102C and -1438G/A) in the 5-HTR2A gene among patients with and without OSAS using DNA from blood samples.
- Results indicated a higher prevalence of males with OSAS, no difference in T102C polymorphism, but a significant association between the -1438G/A polymorphism and OSAS, suggesting a potential genetic link.
Males with obstructive sleep apnea syndrome (OSAS) may present decreased testosterone serum levels because of hypoxemia. To correlate testosterone levels in OSAS patients with laboratory parameters. 103 registries of OSAS patients were reviewed from 2002 to 2009.
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