Publications by authors named "Thi Van Thanh Do"

Treatment with antibiotics is a major risk factor for infection, likely due to depletion of the gastrointestinal microbiota. Two microbiota-mediated mechanisms thought to limit colonization include the conversion of conjugated primary bile salts into secondary bile salts toxic to growth and competition between the microbiota and for limiting nutrients. Using a continuous flow model that simulates the nutrient conditions of the distal colon, we investigated how treatment with 6 clinically used antibiotics influenced susceptibility to infection in 12 different microbial communities cultivated from healthy individuals.

View Article and Find Full Text PDF
Article Synopsis
  • Taking antibiotics can mess up the healthy bacteria in our gut, which might make it easier for infections to happen.
  • The study looked at how different antibiotics changed the bacteria in healthy people's intestines and found that different antibiotics affected them in different ways.
  • Surprisingly, some changes in bacteria and bile salts didn’t necessarily mean a higher chance of infection, showing there are other ways bacteria can control infections without relying just on bile salts.
View Article and Find Full Text PDF

is one of the leading causes of hospital-acquired infections worldwide and presents challenges in treatment due to recurrent gastrointestinal disease after treatment with antimicrobials. The mechanisms by which colonizes the gut represent a key gap in knowledge, including its association with host cells and mucosa. Our results show the importance of flagellin for specific adhesion to mucosal hydrogels and can help to explain prior observations of adhesive defects in flagellin and pilin mutants.

View Article and Find Full Text PDF

The aim of extending shelf-life and maintaining quality is one of the major issues regarding mango fruit preservation. The quality of mango fruits is greatly affected by postharvest factors, especially temperature and fruit treatment. In this study, the effect of coating and storage temperature on the characteristics of mango fruits was investigated.

View Article and Find Full Text PDF

Functional food plants are nature's gift to human beings to help them battle against various ailments for thousands of years. With the global pursuit of improving the quality of life, there is an increasing demand for functional plants in the world's diet. There is a long history of using Gyruna bicolor not only as a vegetable but also as a medicinal herb in East and Southeast Asia.

View Article and Find Full Text PDF