Lewis acid-driven self-assembly of diiridium macrocyclic catalysts imparts substrate selectivity and glutathione tolerance.

Molecular inorganic catalysts (MICs) tend to have solvent-exposed metal centers that lack substrate specificity and are easily inhibited by biological nucleophiles. Unfortunately, these limitations exclude many MICs from being considered for applications. To overcome this challenge, a strategy to spatially confine MICs using Lewis acid-driven self-assembly is presented.

Investigating Effects of COVID-19 Pandemic on the Mental Health of Nursing Students During Remote Learning: An Experience from Dong A University, Vietnam.

Introduction: There was a radically changed in nursing education during the nationwide lockdown due to the COVID-19 outbreaks. The transition to remote learning stressed nursing students in many countries, particularly in Vietnam. However, there is still lacking a novel study to describe the mental characteristics of nursing students in detail.

Customizing Polymers by Controlling Cation Switching Dynamics in Non-Living Polymerization.

Controlling the chain growth process in non-living polymerization reactions is difficult because chain termination typically occurs faster than the time it takes to apply an external trigger. To overcome this limitation, we have developed a strategy to regulate non-living polymerizations by exploiting the chemical equilibria between a metal catalyst and secondary metal cations. We have prepared two nickel phenoxyphosphine-polyethylene glycol variants, one with 2-methoxyphenyl () and another with 2,6-dimethoxyphenyl () phosphine substituents.

Evaluation of dicopper azacryptand complexes in aqueous CuAAC reactions and their tolerance toward biological thiols.

A series of dicopper azacryptand complexes was evaluated in copper-catalysed azide-alkyne cycloaddition (CuAAC) in water at 37 °C. It was found that they showed high activity at concentrations as low as 5 μM. These dinuclear catalysts were more susceptible toward inhibition by cysteine rather than glutathione under the conditions tested.

Screening of Vietnamese medicinal plants for NF-κB signaling inhibitors: assessing the activity of flavonoids from the stem bark of Oroxylum indicum.

Ethnopharmacological Relevance: Seventeen plants used in Vietnamese traditional medicine for the treatment of inflammatory disorders were screened for NF-κB inhibitory activity. Oroxylum indicum, which exhibited activity, was investigated in detail.

Materials And Methods: Forty plant extracts from 17 species were prepared by maceration using dichloromethane and methanol and were tested (10µg/mL) to evaluate their ability to inhibit NF-κB activation using TNF-α-stimulated HEK-293 cells stably transfected with a NF-κB-driven luciferase reporter.

Identification of chromomoric acid C-I as an Nrf2 activator in Chromolaena odorata.

Activation of nuclear factor-erythroid 2-related factor 2 (Nrf2) contributes to several beneficial bioactivities of natural products, including induction of an increased cellular stress resistance and prevention or resolution of inflammation. In this study, the potential of a crude leaf extract of Chromolaena odorata, traditionally used against inflammation and skin lesions, was examined for Nrf2 activation. Guided by an Nrf2-dependent luciferase reporter gene assay, the phytoprostane chromomoric acid C-I (1) was identified as a potent Nrf2 activator from C.

NF-κB inhibitors from Eurycoma longifolia.

The roots of Eurycoma longifolia have been used in many countries of Southeast Asia to alleviate various diseases including malaria, dysentery, sexual insufficiency, and rheumatism. Although numerous studies have reported the pharmacological properties of E. longifolia, the mode of action of the anti-inflammatory activity has not been elucidated.

Switchable multiwavelength erbium doped fiber laser based on a nonlinear optical loop mirror incorporating multiple fiber Bragg gratings.

We propose and experimentally demonstrate a switchable multiwavelength erbium doped fiber laser based on a highly nonlinear dispersion shifted fiber and multiple fiber Bragg gratings. A nonlinear optical loop mirror based on a highly nonlinear dispersion shifted fiber is implemented in the ring laser cavity to stabilize the multiwavelength output at room temperature. Multiple fiber Bragg gratings with the wavelength spacing of 0.

Wavelength-spacing tunable multiwavelength erbium-doped fiber laser based on four-wave mixing of dispersion-shifted fiber.

We experimentally demonstrate a wavelength-spacing tunable multiwavelength erbium-doped fiber laser based on degenerate four-wave mixing in a dispersion-shifted fiber incorporating multiple-fiber Bragg gratings. We have achieved stable operation of the multiwavelength erbium-doped fiber laser, which has 0.8 nm spacing ten-channel lasing wavelengths and a high extinction ratio of more than approximately 45 dB, at room temperature.

Long-distance simultaneous measurement of strain and temperature based on a fiber Raman laser with a single fiber Bragg grating embedded on a quartz plate.

We propose and experimentally demonstrate long-distance remote simultaneous measurement of strain and temperature based on a Raman fiber laser with a single fiber Bragg grating embedded on a quartz plate. A Raman fiber laser output with a high extinction ratio of more than approximately 50 dB is achieved by the fiber grating cavity. In the sensing probe, half of the fiber Bragg grating is fixed steadily on the quartz plate to respond to temperature only, while the other half of the grating is free to respond to both temperature and strain.