Publications by authors named "Thi Minh Huong Le"

Ginsenoside Rh1 is one of major bioactive compounds extracted from red ginseng, which has been increasingly used for enhancing cognition and physical health worldwide. The objective of this study was to review the pharmacological effects of ginsenoside Rh1 in a systematic manner. We performed searches on eight electronic databases including MEDLINE (Pubmed), Scopus, Google Scholar, POPLINE, Global Health Library, Virtual Health Library, the System for Information on Grey Literature in Europe, and the New York Academy of Medicine Grey Literature Report to select the original research publications reporting the biological and pharmacological effects of ginsenoside Rh1 from and studies regardless of publication language and study design.

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Article Synopsis
  • Severe Combined Immunodeficiency (SCID) is life-threatening and requires timely treatment, often delayed due to lack of newborn screening; family history of infant deaths related to SCID contributes to quicker diagnoses.
  • In a study of 147 SCID patients, 94 had genetic diagnoses, revealing 88 different gene mutations, with an average diagnosis age of 4 months and a delay of 2 months in identification.
  • Family history led to earlier presentations and diagnoses, while infections like candidiasis were common but resulted in later diagnosis times; clinicians often missed the significance of family history in clinical assessments.*
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