Foot and Ankle Reconstruction Using Retrograde Lateral Supramalleolar Flap.

 Treatment of soft-tissue defects in the foot and ankle is a challenge. The use of a retrograde lateral supramalleolar flap is a promising technique for reconstruction. This study aims to assess the efficacy and outcomes of the technique.

Clinical Characteristics and Treatment Outcomes of Pediatric Bacterial Skin and Soft Tissue Infections in Central Vietnam: A Prospective Study.

This study examined bacterial skin and soft tissue infections (SSTIs) in pediatric patients at a hospital in Vietnam. An April 2022-June 2023 prospective obsevational study at a Tertiary Paediatric Centre in Vietnam. From We analyzed 87 cases and found that the greatest occurrence rates were reported during the summer season.

Serum Galectin-10: A biomarker for persistent airflow limitation in adult asthmatics.

Background: Inhaled corticosteroids (ICS) are primary anti-inflammatory medications to control eosinophilic airway inflammation, and prevent asthma exacerbation. However, persistent airflow limitation (PAL) presents in some asthmatics even on ICS treatment, leading to lung function decline. Thus, we evaluated clinical associations of serum galectin-10 (Gal10) and galectin-3 (Gal3) levels in adult asthmatics who had maintained anti-asthma medication.

Harnessing potassium peroxymonosulfate activation of WO/diatomite composites for efficient photocatalytic degradation of tetracycline.

The increasing prevalence of pharmaceutical contaminants in aquatic ecosystems poses profound challenges for both environmental sustainability and public health. Addressing this pressing issue requires the development of innovative, cost-effective, and efficient remediation approaches. Here we report the synthesis of WO/diatomite composites and their photocatalytic degradation in conjunction with potassium peroxymonosulfate (PMS) activation.

Visible light photocatalytic NO removal with suppressed poisonous NO byproduct generation over simply synthesized triangular silver nanoparticles coupled with tin dioxide.

The treatment or conversion of air pollutants with a low generation of secondary toxic substances has become a hot topic in indoor air pollution abatement. Herein, we used triangle-shaped Ag nanoparticles coupled with SnO for efficient photocatalytic NO removal. Ag triangular nanoparticles (TNPs) were synthesized by the photoreduction method and SnO was coupled by a simple chemical impregnation process.

Revisionary notes on the genus Brues (Hymenoptera, Braconidae, Macrocentrinae) from Vietnam.

This paper contains descriptions and illustrations of five new species of the genus Brues, 1922, from Vietnam, viz. Long & Pham, ; Long, ; Long & van Achterberg, ; Long & van Achterberg, ; and Long, Additionally, van Achterberg & He is newly recorded for Vietnam's braconid fauna. A checklist and a key to the Oriental and East Palaearctic species is provided and the in-country distribution of the Vietnamese species is given.

Downregulation of otulin induces inflammasome activation in neutrophilic asthma.

Background: Neutrophilic asthma (NA) is a severe asthma phenotype associated with steroid resistance and IL-1β overproduction; however, the exact mechanism remains unclear. Moreover, the dysfunction of TNF-α signaling pathway, a regulator of IL-1β production, was associated with the deficiency of ovarian tumor protease deubiquitinase with linear linkage specificity (otulin) in autoimmune patients.

Objective: We hypothesized that otulin downregulation in macrophages (Mφ) could trigger Mφ activation via the nucleotide-binding domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome signaling pathway.

Immune Cell-Mediated Autoimmune Responses in Severe Asthma.

Severe asthma (SA) has heterogeneous inflammatory phenotypes characterized by persistent airway inflammation (eosinophilic and/or neutrophilic inflammation) and remodeling. Various immune cells (eosinophils, neutrophils, and macrophages) become more activated and release inflammatory mediators and extracellular traps, damaging the protective barrier of airway epithelial cells and further activating other immune and structural cells. These cells play a role in autoimmune responses in asthmatic airways, where the adaptive immune system generates autoantibodies, inducing immunoglobulin G-dependent airway inflammation.

ST2-Mediated Neutrophilic Airway Inflammation: A Therapeutic Target for Patients With Uncontrolled Asthma.

Purpose: Suppression of tumorigenicity 2 (ST2) has been proposed as the receptor contributing to neutrophilic inflammation in patients with type 2-low asthma. However, the exact role of ST2 in neutrophil activation remains poorly understood.

Methods: A total of 105 asthmatic patients (classified into 3 groups according to control status: the controlled asthma [CA], partly-controlled asthma [PA], and uncontrolled asthma [UA] groups), and 104 healthy controls were enrolled to compare serum levels of soluble ST2 (sST2) and interleukin (IL)-33.

Intra-Articular Calcaneus Osteoid Osteoma With an Ankle Varus and a Red-Brown Synovial Fluid in the Affected Joint, a Case Report.

Background: Only one article described ankle varus as a typical symptom in the late stage of the intra-articular osteoid osteoma of the calcaneus. And the red-brown color of synovial fluid in the affected joint hasn't been reported. This report shows a patient with intra-articular osteoid osteoma of the calcaneus who had the 2 above symptoms.

Microplastics in sediments from urban and suburban rivers: Influence of sediment properties.

Although sediments are considered to be a major sink for microplastics (MP), there is still a relative lack of knowledge on the factors that influence the occurrence and abundance of MP in riverine sediments. The present study investigated the occurrence and distribution of MP in riverine sediments collected at twelve sites representative of different populated and urbanized rivers (To Lich, Nhue and Day Rivers) located in the Red River Delta (RRD, Vietnam, during dry and rainy seasons. MP concentrations ranged from 1600 items kg dw to 94,300 items kgdw.

Contribution of monocyte and macrophage extracellular traps to neutrophilic airway inflammation in severe asthma.

Background: Increased blood/sputum neutrophil counts are related to poor clinical outcomes of severe asthma (SA), where we hypothesized that classical monocytes (CMs)/CM-derived macrophages (Mφ) are involved. We aimed to elucidate the mechanisms of how CMs/Mφ induce the activation of neutrophils/innate lymphoid cells (ILCs) in SA.

Methods: Serum levels of monocyte chemoattractant protein-1 (MCP-1) and soluble suppression of tumorigenicity 2 (sST2) were measured from 39 patients with SA and 98 those with nonsevere asthma (NSA).

Tissue Inhibitor of Metalloproteinase-1 Enhances Eosinophilic Airway Inflammation in Severe Asthma.

Purpose: Severe asthma (SA) is characterized by persistent airway inflammation and remodeling, followed by lung function decline. The present study aimed to evaluate the role of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the pathogenesis of SA.

Methods: We enrolled 250 adult asthmatics (54 with SA and 196 with non-SA) and 140 healthy controls (HCs).

Role of club cell 16-kDa secretory protein in asthmatic airways.

Background: Club cell 16-kDa secretory protein (CC16) is a pneumoprotein and functions as an anti-inflammatory or antioxidant protein. However, altered levels of serum CC16 as well as their effect on airways inflammation have not been fully evaluated.

Methods: We recruited 63 adult asthmatics on maintenance medications and 61 healthy controls (HCs).

Endocrine-disrupting chemical exposure augments neutrophilic inflammation in severe asthma through the autophagy pathway.

Corticosteroid resistance, progressive lung function decline, and frequent asthma exacerbations are the hallmarks of neutrophilic asthma (NA). However, the potential contributors and their mechanisms of NA aggravation have not yet been fully clarified. This study was conducted to assess the precise mechanism and inflammatory effects of endocrine-disrupting chemicals using mono-n-butyl phthalate (MnBP) on an NA model.

Photoelectrochemical water oxidation over TiO nanotubes modified with MoS and g-CN.

TiO nanotube arrays (TNAs) have been studied for photoelectrochemical (PEC) water splitting. However, there are two major barriers of TNAs, including a low photo-response and the fast charge carrier recombination in TNAs, leading to poor photocatalytic efficiency. Through a comparison of MoS/TNAs and g-CN/TNAs, it was found that TNAs modified with MoS and g-CN exhibited a current density of, respectively, 210.

Stability of the knee after posterior cruciate ligament reconstruction using peroneus longus tendon graft with three femoral insertion sites. A cadaveric study.

Introduction: Many kinds of grafts were used for single-bundle reconstruction of the posterior cruciate ligament (PCL). Recently, the peroneus longus tendon (PLT) was used in some clinical reports. This study aimed to test the best position of the femoral insertion in the case of using PLT for PCL reconstruction.

Lateral supramalleolar flap for soft-tissue coverage of ankle and foot defects.

The reconstruction of soft tissue defects in the foot and ankle remains a big challenge due to the anatomical characteristics of this area. This study evaluated the long-term effectiveness of covering by lateral supramalleolar flap in patients with soft tissue defects around the ankle and foot. We conducted a retrospective study from January 2017 to December 2020 at the Hospital for Traumatology and Orthopedics, Ho Chi Minh City, Vietnam.

Selective serotonin reuptake inhibitors and the risk of type 2 diabetes mellitus in youths.

Background: Selective serotonin reuptake inhibitors (SSRIs) have been associated with type 2 diabetes mellitus (T2DM) in youths, possibly via 5-HT, H receptors and serotonin transporter (SERT). SSRIs have similar affinity for SERT but variable affinity for 5-HT and H. This study assessed whether SSRIs with strong affinity for 5-HT and H (relative to SERT) were associated with T2DM risk compared with weak-affinity SSRIs.

Dynamic Models of Within-Herd Transmission and Recommendation for Vaccination Coverage Requirement in the Case of African Swine Fever in Vietnam.

African swine fever (ASF) is a highly contagious disease that is caused by the ASF virus (ASFV) with a high fatality rate in domestic pigs resulting in a high socio-economic impact. The pig business in Vietnam was recently affected by ASF for the first time. This study thus aimed to develop a disease dynamic model to explain how ASFV spreads in Vietnamese pig populations and suggest a protective vaccine coverage level required to prevent future outbreaks.

Enhancing Green Product Generation of Photocatalytic NO Oxidation: A Case of WO Nanoplate/g-CN S-Scheme Heterojunction.

Nitric oxide (NO) removal by photocatalytic oxidation over g-CN has achieved more efficient results. However, there is a concern about the high NO-to-NO conversion yield of products, which is not suitable for the photocatalytic NO reaction. In this study, we modify g-CN by WO nanoplates for the first time for photocatalytic NO oxidation over a WO/g-CN composite to enhance the green product selectivity under atmospheric conditions.

Down-regulated surfactant protein B in obese asthmatics.

Background: Obesity is a common comorbid condition in adult asthmatics and known as a feature of asthma severity. However, the molecular mechanism under obesity-induced inflammation has not yet been fully understood.

Objective: Considering the essential role of hydrophobic surfactant protein B (SP-B) in lung function, SP-B was targeted to examine its involvement in the development of obesity-induced airway inflammation in asthmatics.

Tin dioxide nanomaterial-based photocatalysts for nitrogen oxide oxidation: a review.

Semiconducting SnO photocatalyst nanomaterials are extensively used in energy and environmental research because of their outstanding physical and chemical properties. In recent years, nitrogen oxide (NO ) pollutants have received particular attention from the scientific community. The photocatalytic NO oxidation will be an important contribution to mitigate climate change in the future.