Publications by authors named "Theresia I Budhy"

Article Synopsis
  • This study investigates the use of nanoparticle-based rice husk liquid smoke (n-RHLS) as a potential treatment for periodontitis in rats, focusing on its effects on key proteins involved in bone health.
  • The experiment involved inoculating rats with bacteria to induce periodontitis, followed by treatment with n-RHLS and evaluation of osteoprotegerin (OPG), RANK, and RANKL levels through immunohistochemical staining.
  • Results showed a significant increase in OPG and a notable decrease in RANKL expression after 7 days of n-RHLS treatment, suggesting it could be beneficial in promoting periodontal tissue health by modulating these proteins.
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In recent years, liquid smoke rice husk (LSRH) has shown its therapeutic potency to diabetes, wound healing, stomatitis, and periodontitis. The phenol, 6-octadecenoic acid, oleic acid, and 9-octadecanoic acid were responsible for their therapeutic effect. The LSRH also demonstrated their potential for infectious diseases such as coronavirus disease (COVID-19).

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Background: Biodegradable hydrogel scaffold is one of the crucial characteristics that determine the success of pulp regeneration. The degradation should be suitable for the growth of new tissue establishment. The aim of this study is to synthesize and compare the novel biodegradable hydrogel scaffold based on hydroxyapatite (HAp) eggshell, collagen, and epigallocatechin-3-gallate (HAp-Col-EGCG) with different HAp concentrations .

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Objectives:  Liquid smoke rice husk has been researched and proved to consist of antibacterial, analgesic, anti-inflammatory, and growth factor stimulatory properties. By these complex properties, the liquid smoke rice hull is able to purpose as a novel coronavirus disease 2019 (COVID-19) inhibitor. The research was conducted to analyze the role of the dominant compound in rice husk liquid smoke against one of the main proteases in complex with inhibitor N3 of COVID-19 and 6LU7 protein data bank (PDB) ID.

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Objective:  Utilization of liquid smoke rice husk can be used as an alternative treatment because of the antimicrobial properties. Advances in drug delivery systems are increasingly developing to increase the bioavailability of drugs and reduce the side effects of these drugs, namely nanoparticles. In this study, nanoparticles of liquid smoke rice husk (nLSRH) were tested the antimicrobial against .

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Objective:  Rice husk liquid smoke nanoparticles have the potential to be developed as a drug because they have anti-inflammatory effects that can modulate the process of osteoblast stimulation through osteoblast stimulation by thorough small size and enter cells easily. The osteoblast is the key of alveolar regeneration in periodontitis treatment. This present study analyzed the differences of liquid smoke rice husk and nanoparticles of liquid smoke rice husk on osteoblast viability as periodontitis treatment MATERIALS AND METHODS:  The liquid smoke rice husk was obtained from the pyrolysis process.

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Objective:  The aim of this article is to analyze and compare the presence of single-nucleotide polymorphisms (SNPs) of and in class II and class III Javanese populations.

Materials And Methods:  Cephalometric radiographs from total 63 patients of class II and III were analyzed. SNP analysis was performed based on both and sequences amplified from total DNA of patients' fresh blood.

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Nonsurgical treatment such as scaling and root planing has been the main therapy of periodontal management. However, some individuals are nonresponsive with only mechanical therapy. Rice hull liquid smoke (RH-LS) with higher of phenolic compound supposed to interfere with inflammation process.

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Introduction: Due to the increasing prevalence of periodontitis within the general population, it is important to study the progress and stages of periodontal disease and the efficacy of periodontal treatment through and experiments. Mouse periodontitis models are important in many studies. This study presents the findings from a scoping review of the current literature regarding the available method to produce mouse periodontitis models using whole bacteria.

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Objectives: The purpose of this study was to analyze the effects of rice husk liquid smoke in -induced periodontitis in the inflammatory and proliferation marker such as nuclear factor kappa β (NF-kB), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), transforming growth factor-β (TGF-β), fibroblast growth factor 2 (FGF2), collagen type 1 (COL-1) expression, and the number of macrophages, lymphocytes, and fibroblasts.

Materials And Methods: Rice husk liquid smoke is obtained by the pyrolysis process. -induced periodontitis in 20 μL phosphate-buffered saline containing 1 × 10 CFU was injected into the lower anterior gingival sulcus of Wistar rats.

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Background: Squamous Cell Carcinoma (SCC) is a type of cancer that is often found in oral cavity and areas of the head and neck. Viruses are major etiological factors through production of factors that can disturb proliferation and apoptosis regulators such as p53i, c-myc and bcl-2. This study aimed to determine the molecular grading of oral squamous cell carcinoma (OSCCs) infected with the Epstein-Barr Virus (EBV).

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