Publications by authors named "Therese-Marie Sartoris"

Type 2 diabetes mellitus (T2DM), characterized by hyperglycemia and dyslipidemia, leads to nonproliferative diabetic retinopathy (NPDR). NPDR is associated with blood-retina barrier disruption, plasma exudates, microvascular degeneration, elevated inflammatory cytokine levels, and monocyte (Mo) infiltration. Whether and how the diabetes-associated changes in plasma lipid and carbohydrate levels modify Mo differentiation remains unknown.

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Article Synopsis
  • Tourette syndrome primarily affects children and adolescents, yet its impact on their daily lives has not been thoroughly researched.
  • A study involving 62 adolescents analyzed their experiences at school, home, and socially, focusing on which aspects of Tourette syndrome presented the most challenges and their future outlook.
  • Key findings indicated that tic severity worsened school challenges, comorbidities impacted social interactions, and younger patients expressed more negative feelings about their futures, with social stigma being a recurring theme.
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The classical aortic ring model is well suited for deciphering pro-angiogenic processes. Here, we propose simple modifications of the standard protocol to study various anti-angiogenic processes from growth arrest to capillary degeneration. Aortic rings are cultured under basal conditions for 6 days to allow physiological vessel sprouting and then split into treatment groups to follow capillary growth or degeneration for an additional 2 days.

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