Commingled Fluids in Abandoned Boreholes: Proximity Analysis of a Hidden Liability.

The interactions between old abandoned wellbores of suspect well integrity with hydraulic fracturing (HF), enhanced oil recovery (EOR), or salt water disposal (SWD) operations can result in upward leakage of deep aqueous liquids into overlying aquifers. This potential for upward fluid migration is largely unquantified as monitoring abandoned wells is rarely done, and leakage may go unnoticed especially when in deeper aquifers. This study performs a proximity analysis between old abandoned wells and HF, EOR, and SWD wells, and identifies commingled old abandoned wellbores, which are those wells where groundwater may flow from one aquifer to one or more other aquifers, to identify the locations with the greatest potential for upward aqueous fluid migration at three study sites in the Western Canadian Sedimentary Basin.

Procalcitonin and cytokine profiles in engraftment syndrome in pediatric stem cell transplantation.

Background: Diagnosis of engraftment syndrome (ES) following allogeneic hematopoietic stem cell transplantation (HSCT) can be a challenge due to the systemic presentation and alternative etiologies. With a goal of establishing biomarkers to more accurately distinguish ES, we prospectively analyzed levels of cytokines during HSCT.

Procedures: We performed a prospective study of children ≤21 years who underwent allogeneic HSCT.

Risk factors for molecular detection of adenovirus in pediatric hematopoietic stem cell transplantation recipients.

Adenovirus (AdV) infections are a major cause of morbidity and mortality in patients undergoing hematopoietic stem cell transplantation (HSCT). To evaluate the use of molecular AdV testing in HSCT at our institution and identify risk factors for AdV viremia and disease, we performed a retrospective cohort study of all HSCT recipients who had undergone AdV polymerase chain reaction testing over a 2-year period. Two cohorts were identified: cohort 1, comprising patients testing positive for AdV (n = 7) and cohort 2, comprising patients testing negative (n = 36).