Publications by authors named "Theresa Sexton"
Article Synopsis
- The study aimed to identify the most effective antidysrhythmic drug for converting recent-onset atrial fibrillation (AF) back to normal rhythm within 24 hours.
- Researchers conducted a systematic review, analyzing data from 30 randomized controlled trials involving 2,785 patients, comparing various antidysrhythmic drugs and their effectiveness in achieving cardioversion.
- The analysis concluded that while drugs like vernakalant and flecainide showed promise, there wasn't enough strong evidence to definitively recommend the best treatment, indicating the need for further research in this area.
Study Objective: We conduct a systematic review and Bayesian network meta-analysis to indirectly compare and rank antidysrhythmic drugs for pharmacologic cardioversion of recent-onset atrial fibrillation and atrial flutter in the emergency department (ED).
Methods: We searched MEDLINE, EMBASE, and Web of Science from inception to March 2019, limited to human subjects and English language. We also searched for unpublished data.