Publications by authors named "Theresa Noll"
Article Synopsis
- Scientists looked at two types of surgeries to help guys with urinary problems caused by an enlarged prostate: aquablation and a procedure called HoLEP.
- Both surgeries helped reduce symptoms, but HoLEP took less time and had fewer complications.
- Aquablation showed some short-term benefits for things like ejaculation and bladder control, but over time, HoLEP proved to be better overall.
Background: T helper (Th) 17 cells are a highly plastic subset of T cells, which in the context of neuroinflammation, are able to acquire pathogenic features originally attributed to Th1 cells (resulting in so called ex-Th17 cells). Thus, a strict separation between the two T cell subsets in the context of experimental autoimmune encephalomyelitis (EAE) is difficult. High variability in culture and EAE induction protocols contributed to previous conflicting results concerning the differential contribution of Th1 and Th17 cells in EAE.
View Article and Find Full Text PDFIn many tumors, including prostate cancer, anti-apoptotic members of the Bcl-2 family are overexpressed and cause cell death resistance, which is a typical hallmark of cancer. Different therapeutic approaches, therefore, aim to restore the death mechanisms for enhanced apoptosis. Our recombinant immunotoxin D7(VL-VH)-PE40 is composed of the scFv D7(VL-VH) against the prostate-specific membrane antigen (PSMA) on the surface of prostate cancer cells and of the cytotoxic domain of the bacterial toxin Pseudomonas Exotoxin A (PE40).
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