Publications by authors named "Theresa M Y Lee"

Introduction: Perinatal depression and anxiety are public health concerns affecting approximately 1 in 10 women in Singapore, with clear evidence of association with various adverse outcomes in mother and child, including low birthweight, preterm birth and negative impact on infant neurodevelopment, temperament and behaviour. A workgroup was formed to develop recommendations to address the perinatal mental health needs of women with depression and anxiety. The approach was broad-based and aimed to incorporate holistic methods that would be readily applicable to the network of care providers supporting childbearing women.

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Article Synopsis
  • Perinatal depression is a common mental health issue during and after pregnancy, potentially impacting both mothers and their newborns, with genetic factors and hormonal changes possibly contributing to the risk.
  • A case-control study was conducted with 725 patients of Chinese descent to analyze gene variants related to perinatal depression, comparing those diagnosed with depression to control subjects with low depression scores.
  • Results showed that while certain gene variants (CRHR1 and GR) didn't have a significant link to perinatal depression, one variant (CRHR1 rs242941) did have a notable association with family history of mental illness and menstrual regularity.
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Objectives: The impact of command hallucinations on patients and the determinants of patients' compliance with them are still poorly understood. The extant literature is also divided on their association with violence. This study aimed to establish the prevalence of command hallucinations and to identify the factors that affect compliance with the commands, together with patients' coping methods.

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