Chronic Stress and Ovarian Function in Female Childhood Cancer Survivors.

Objectives: To explore the relationships among perceived stress, biomarkers of hypothalamic-pituitary-adrenal (HPA) activity, gonadotropin levels, and anti-Müllerian hormone (AMH) in female childhood cancer survivors (CCSs).

Sample & Setting: 24 female CCSs from the Royal Hospital for Sick Children in Edinburgh, Scotland, were included in the study.

Methods & Variables: Perceived stress was measured using the Perceived Stress Scale.

Genomics of Reproductive Traits and Cardiometabolic Disease Risk in African American Women.

Background: Age at menarche and age at natural menopause occur significantly earlier in African American women than in other ethnic groups. African American women also have twice the prevalence of cardiometabolic disorders related to the timing of these reproductive traits.

Objectives: The objectives of this integrative review were to (a) summarize the genome-wide association studies of reproductive traits in African American women, (b) identify genes that overlap with reproductive traits and cardiometabolic risk factors in African American women, and (c) propose biological mechanisms explaining the link between reproductive traits and cardiometabolic risk factors.

Exploring the Ovarian Reserve Within Health Parameters: A Latent Class Analysis.

The process of ovarian aging is influenced by a complex and poorly understood interplay of endocrine, metabolic, and environmental factors. The purpose of this study was to explore the feasibility of using latent class analysis to identify subgroups based on cardiometabolic, psychological, and reproductive parameters of health and to describe patterns of anti-Müllerian hormone levels, a biomarker of the ovarian reserve, within these subgroups. Sixty-nine lean (body mass index [BMI] ⩽ 25 kg/m) and severely obese (BMI ⩾ 40 kg/m) postpartum women in Edinburgh, Scotland, were included in this exploratory study.

Anti-Müllerian Hormone Levels and Urinary Cortisol in Women With Chronic Abdominal Pain.

Objective: To explore the association of hypothalamic-pituitary-adrenal activity with ovarian functioning in women with and without chronic abdominal pain (CAP).

Design And Setting: A secondary data analysis was performed with data from female participants in a natural history protocol at the National Institutes of Health.

Participants: A total of 36 women (age range = 19-39 years, mean = 27.