Living up to expectations? A simulation study evaluating methods used to detect sudden gains and sudden losses.

Sudden gains and sudden losses are abrupt, large changes in symptom severity between two consecutive psychotherapy sessions. Sudden gains (i.e.

A Tutorial Introduction to Heterogeneous Treatment Effect Estimation with Meta-learners.

Psychotherapy has been proven to be effective on average, though patients respond very differently to treatment. Understanding which characteristics are associated with treatment effect heterogeneity can help to customize therapy to the individual patient. In this tutorial, we describe different meta-learners, which are flexible algorithms that can be used to estimate personalized treatment effects.

Comprehensive ABA-based interventions in the treatment of children with autism spectrum disorder - a meta-analysis.

Background: Many studies display promising results for interventions that are based on Applied Behavior Analysis (ABA) in the treatment of autism spectrum disorder (ASD).

Methods: This meta-analysis assessed the effects of such treatments on developmental outcomes in children with ASD and on parental stress based on 11 studies with 632 participants.

Results: Compared to treatment as usual, minimal or no treatment, comprehensive ABA-based interventions showed medium effects for intellectual functioning (standardized mean difference SMD = 0.