Clinically aggressive "low-grade" uterine carcinosarcoma: A case report.

•We present a case of uterine carcinoma with low-grade carcinomatous and sarcomatous components.•The tumor is likely a rare biphasic form of carcinosarcoma.•Molecular profiling suggests that it is a Type I endometrial cancer.

Safety and efficacy of testosterone replacement therapy in adolescents with Klinefelter syndrome.

Purpose: We investigated the safety and tolerability of testosterone replacement therapy in adolescents with Klinefelter syndrome.

Materials And Methods: We reviewed the medical records of all consecutive adolescents with Klinefelter syndrome evaluated between 2007 and 2012. Patients receiving testosterone replacement and aromatase inhibitor therapy were identified.