Maternal Geophagy of Calabash Chalk on Foetal Cerebral Cortex Histomorphology.

Background: Calabash chalk, a kaolin-base substance is a common geophagic material mostly consumed by pregnant women. This study investigated its effect on the histomorphology of the foetal cerebral cortex.

Methods: Twelve gestating Wistar rats were divided equally into groups 1 and 2.

Cerebellar neurohistology and behavioural effects of gongronema latifolium and Rauwolfia vomitoria in mice.

Rauwolfia vomitoria and Gongronema latifolium are medicinal herbs used for the treatment of hypertension, malaria, mental and intestinal disorders. G. latifolium is known to prevent the side effects reported for R.

Evaluation of calabash chalk effect on femur bone morphometry and mineralization in young wistar rats: A pilot study.

Background: Calabash chalk, a popularly consumed geophagic material in Nigeria has been reported to contain lead, arsenic, alpha lindane, endrin, and endosulfan 11 among other pollutants.

Aim: The continuous exposure of young children to this chalk necessitated this study on the bone morphometry and mineralization in young Wistar rats.

Materials And Methods: Fourteen young (weanling) Wistar rats of both sexes weighing 54-72 g were assigned into two groups of seven animals each.

Teratogenic Effect of Crude Ethanolic Root Bark and Leaf Extracts of Rauwolfia vomitoria (Apocynaceae) on Nissl Substances of Albino Wistar Rat Fetuses.

Rauwolfia vomitoria is a plant used for the treatment of insanity. The possible adverse effects of crude ethanolic root bark and leaf extract of the plant on Nissl substances of albino Wistar rat fetuses were studied using 25 mature female Wistar rats. The animals were divided equally into 5 groups, labeled A, B, C, D, and E.

Effect of calabash chalk on the histomorphology of the gastro-oesophageal tract of growing wistar rats.

Background: Calabash chalk is a naturally occurring mineral consumed by members of some Nigerian communities for pleasure and by pregnant women as a remedy for morning sickness. The consumption of this geophagic material motivated our interest on the effect of the chalk on the histomorphology of the gastro-oesophageal tract.

Methods: Twenty-eight young Wistar rats, 4 weeks old, were divided into 4 groups of equal size.

Comparative study of teratogenic potentials of crude ethanolic root bark and leaf extract of Rauwolfia vomitoria (apocynaceae) on the fetal heart.

Background: Rauwolfia vomitoria, a tropical shrub, is a medicinal plant used in the treatment of a variety of ailments. It is popular to the locals because of its anti-hypertensive and sedative properties.

Aim: This is to find the probable teratogenic effects of ethanolic leaf and root bark extracts of Rauwolfia vomitoria on the morphological and histological features of the fetal heart.

The effect of calabash chalk on some hematological parameters in female adult Wistar rats.

Objective: Calabash chalk is a naturally occurring mineral consumed among the Nigerian community for pleasure and commonly by pregnant women as a remedy for morning sickness. Reports have shown that it contains different toxic substances, with lead being the most abundant. This study was therefore undertaken to ascertain the effect of two commonly available preparations of this chalk on some hematological parameters.

Prevalence of congenital malformations in Cross River and Akwa Ibom states of Nigeria from 1980-2003.

A retrospective study was conducted on the prevalence of congenital malformations in Cross River and Akwa Ibom states of Nigeria from 1980-2003. These states lie in the South-South geopolitical zone of Nigeria. The aim of the study was to determine the percentage of occurrence of birth defects and provide reference data for this part of the country.