The Eyewitness Community Survey: An Engaging Citizen Science Tool to Capture Reliable Data while Improving Community Participants' Environmental Health Knowledge and Attitudes.

Many youths and young adults have variable environmental health knowledge, limited understanding of their local environment's impact on their health, and poor environmentally friendly behaviors. We sought to develop and test a tool to reliably capture data, increase environmental health knowledge, and engage youths as citizen scientists to examine and take action on their community's challenges. The Eyewitness Community Survey (ECS) was developed through several iterations of co-design.

Environmental Health Knowledge Does Not Necessarily Translate to Action in Youth.

Environmental challenges pose serious health problems, especially for children, and lay public action is lacking. This study sought to characterize the relationship between environmental health knowledge and behavior in youth. A cross-sectional, descriptive survey with quantitative and qualitative questions was conducted.

Nasal DNA methylation is associated with childhood asthma.

Aim: We aim to study DNA methylation (DNAm) variations associated with childhood asthma.

Methods: Nasal DNAm was compared between sibling pairs discordant for asthma, 29 sib pairs for genome-wide association studies and 54 sib pairs for verification by pyrosequencing. Associations of methylation with asthma symptoms, allergy and environmental exposures were evaluated.

Detection of articular pathology of the distal aspect of the third metacarpal bone in thoroughbred racehorses: comparison of radiography, computed tomography and magnetic resonance imaging.

Objective: To compare digital radiography (DR), computed tomography (CT), and magnetic resonance imaging (MRI) for detection of pathology of the distal aspect of the third metacarpal bone (MC3) and to assess whether arthrography would improve detection of articular cartilage or subchondral bone cracking.

Study Design: Cross-sectional study.

Sample Population: Limb specimens from 17 Thoroughbred horses after catastrophic injury and 4 age-matched control horses.

Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006-2008).

Objective: To evaluate efficacy and adverse effects of leflunomide for the treatment of naturally occurring immune-mediated polyarthritis (IMPA) in dogs.

Design: Retrospective case series.

Animals: 14 dogs with cytologically confirmed IMPA.

Seasonal variation in detection of bacterial DNA in arthritic stifle joints of dogs with cranial cruciate ligament rupture using PCR amplification of the 16S rRNA gene.

An underappreciated cause and effect relationship between environmental bacteria and arthritis may exist. Previously, we found that stifle arthritis in dogs was associated with the presence of environmental bacteria within synovium. Cranial cruciate ligament rupture (CCLR) is often associated with stifle arthritis in dogs.

Mechanical loading of a long bone induces plasticity in sensory input to the central nervous system.

Although the skeleton is extensively innervated by sensory nerves, the importance of this innervation to skeletal physiology is unclear. Neuronal connectivity between limbs is little studied and likely underestimated. In this study, we examined the effect of bone loading on spinal plasticity in young male Sprague-Dawley rats, using end-loading of the ulna and transynaptic tracing with the Bartha pseudorabies virus (PRV).