Publications by authors named "Theophilus I Umeizudike"
Background: Periodontal diseases are chronic and inflammatory in nature, and have been associated with hypertension, a major risk factor for cardiovascular diseases. Hypertension is prevalent among Nigerians. However, controlled studies on the relationship between hypertension and periodontal disease in Nigeria are limited.
View Article and Find Full Text PDFDespite positive economic forecasts, stable democracies, and reduced regional conflicts since the turn of the century, Africa continues to be afflicted by poverty, poor infrastructure, and a massive burden of communicable diseases such as HIV, malaria, tuberculosis, and diarrheal illnesses. With the rising prevalence of chronic kidney disease and kidney failure worldwide, these factors continue to hinder the ability to provide kidney care for millions of people on the continent. The International Society of Nephrology Global Kidney Health Atlas project was established to assess the global burden of kidney disease and measure global capacity for kidney replacement therapy (dialysis and kidney transplantation).
View Article and Find Full Text PDFArticle Synopsis
- Lupus nephritis (LN) can lead to severe complications like kidney failure and death, with limited comparative data on treatment efficacy between mycophenolate mofetil (MMF) and intravenous cyclophosphamide (IVCYC) in African populations.
- A retrospective study in Cape Town analyzed 84 patients with biopsy-confirmed proliferative LN, finding no significant differences in remission or relapse rates after treatment with MMF or IVCYC, although baseline kidney function predicted mortality risk.
- The research indicates that both induction therapies yield comparable outcomes for patients in South Africa, but emphasizes the need for a prospective, randomized study for a more thorough evaluation of these treatments.
Background: The burden of symptoms and other concerns in chronic kidney disease (CKD) is known to be high, adversely affecting the quality of life of the growing number of those with this condition in developing countries. In this paper, we describe the protocol of a longitudinal observational study among people living with CKD. The study is developed to assess the bio-psychosocial factors associated with palliative care symptoms and concerns, and pattern of health services usage among Nigerians with stages 3-5 CKD.
View Article and Find Full Text PDFBackground: Long-term treatment of common chronic cardiac conditions such as hypertension with calcium channel blockers (CCBs) has long been associated with gingival hyperplasia. This oral side effect may affect esthetics and function, yet often overlooked and therefore underreported among Nigerians.
Aim: This study aimed to determine the association of CCBs with gingival overgrowth (GO) in hypertensive patients.
Background: The burden of chronic kidney disease (CKD) in Nigeria is quite alarming. The prevalence of CKD ranges from 11 - 23.5%.
View Article and Find Full Text PDFBlood pressure gradients and cardiovascular risk factors in urban and rural populations in Abia State South Eastern Nigeria using the WHO STEPwise approach.
PLoS One
June 2014
Background: Developing countries of sub-Saharan Africa (SSA) face a double burden of non-communicable diseases (NCDs) and communicable diseases. As high blood pressure (BP) is a common global cardiovascular (CV) disorder associated with high morbidity and mortality, the relationship between gradients of BP and other CV risk factors was assessed in Abia State, Nigeria.
Methods: Using the WHO STEPwise approach to surveillance of chronic disease risk factors, we conducted a population-based cross-sectional survey in Abia state, Nigeria from August 2011 to March 2012.
Article Synopsis
- The study aimed to investigate the prevalence of abdominal obesity in Abia State, Nigeria, due to its links with health issues like diabetes and hypertension.
- The research involved screening 2,807 participants using waist circumference measurements and body mass index (BMI) assessments.
- Findings revealed a 21.75% prevalence of abdominal obesity overall, with 39.2% in women and only 3.2% in men, indicating a significant health concern in the region.
Aim: To determine the relevance of routine blood pressure (BP) measurement in patients attending the dental clinic.
Materials And Methods: This was a retrospective survey of patients who attended the dental clinic in the Preventive Dentistry Department of a tertiary Hospital in Lagos, Nigeria over an eighteen month period. Data retrieved from the patient's hospital records included age, sex, BP and history of hypertension.