A pharmacological characterization of Cannabis sativa chemovar extracts.

Background: Cannabis contains Δ-tetrahydrocannabinol (Δ-THC) and cannabidiol (CBD) as the primary constituents responsible for pharmacological activity. However, there are numerous additional chemically-related structures to Δ-THC and CBD that are pharmacologically active and may influence the pharmacological properties of Δ-THC and CBD. This study chemically characterized the cannabinoid constituents in a series of cannabis chemovar extracts and investigated the potential cannabinoid entourage effect in two behavioral assays.