Publications by authors named "Theodore Rader"

Transplant infectious disease (TID) clinicians are integral to the pre-transplantation evaluation. Pre-transplant evaluations allow clinicians to assess risk factors for latent infections and relevant exposures to potential pathogens, address immunizations, and optimize patients' health and understanding of life after transplant. However, there is not a standardized approach to the pre-transplant evaluation.

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Article Synopsis
  • The study evaluated how selective whole-genome sequencing (WGS) can help in investigating COVID-19 outbreaks in healthcare settings.
  • Researchers conducted a mixed-methods study across 8 facilities, analyzing 17 COVID-19 clusters and providing real-time WGS results to Infection Prevention and Control (IPC) teams.
  • The findings showed that WGS identified previously unknown transmission pathways in many cases, significantly altering how IPC teams understood and responded to the outbreaks.
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Purpose Of Review: Syndromic multiplex polymerase chain reaction (mPCR) panels offer the antimicrobial steward a rapid tool for optimizing and de-escalating antimicrobials. In this review, we analyze the role of syndromic mPCR in respiratory, gastrointestinal, and central nervous system infections within the context of antimicrobial stewardship efforts.

Recent Findings: For all mPCR syndromic panels, multiple studies analyzed the pre-and-post implementation impact of mPCR on antimicrobial utilization.

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