Prevalence and significance of subretinal drusenoid deposits (reticular pseudodrusen) in age-related macular degeneration.

Purpose: To determine the prevalence and significance of subretinal drusenoid deposits (reticular pseudodrusen) among patients with age-related macular degeneration (AMD).

Design: A prospective study with a nested case-control study of consecutive patients with AMD seen in a referral retinal practice.

Participants: There were 153 patients with AMD, 131 of whom had > or =1 eye with late AMD, which was defined as either central geographic atrophy or choroidal neovascularization.

Comparison between a fundus camera and scanning laser ophthalmoscope in acquiring fluorescence emission in vitro.

Background And Objectives: To compare the fluorescence measurements acquired from a fundus camera with those from a scanning laser ophthalmoscope (SLO) camera.

Materials And Methods: The fundus camera and the SLO camera were used to capture images of 29 cuvettes each containing serially diluted sodium fluorescein dye in normal saline. The intensity levels of the resulting images were plotted as a function of concentration to compare the two cameras.