Optofluidics is dedicated to achieving integrated control of particle and fluid motion, particularly on the micrometer scale, by utilizing light to direct fluid flow and particle motion. The field has seen significant growth recently, driven by the concerted efforts of researchers across various scientific disciplines, notably for its successful applications in biomedical science. In this review, we explore a range of optofluidic architectures developed over the past decade, with a primary focus on mechanisms for precise control of micro and nanoscale biological objects and their applications in sensing.
View Article and Find Full Text PDFDouble Nanohole Plasmonic Tweezers (DNH) have emerged as a powerful approach for confining light to sub-wavelength volume, enabling the trapping of nanoscale particles much smaller than the wavelength of light. However, to circumvent plasmonic heating effects, DNH tweezers are typically operated off-resonance, resulting in reduced optical forces and field enhancements. In this study, we introduce a novel DNH design with a reflector layer, enabling on-resonance illumination while minimizing plasmonic heating.
View Article and Find Full Text PDFOptical trapping with plasmonic double nanohole (DNH) apertures has proven to be an efficient method for trapping sub-50 nm particles due to their suppressed plasmonic heating effect and very high electric field enhancement in the gap region of the aperture. However, plasmonic tweezers are generally diffusion-limited, requiring particles to diffuse down to a few tens of nanometres from the high field enhancement regions before they can be trapped. The loading of target particles to the plasmonic hotspots can take several minutes for diluted samples.
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