Publications by authors named "Theodorakakos A"

The present paper focuses on the simulation of the growth and collapse of a bubble in the vicinity of a wall. Both liquid and gas phases are assumed compressible, and their interaction is handled with the volume-of-fluid method. The main interest is to quantify the influence of the induced shear stress and pressure pulse in the vicinity of the wall for a variety of bubble sizes and bubble-wall distances.

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Article Synopsis
  • The study investigates the functional behavior and hemodynamic characteristics of two common bioprosthetic valves: the Edwards SAPIEN and the Medtronic CoreValve, using aortic models.
  • The analysis revealed distinct aortic flow patterns, with the Medtronic valve causing more persistent vortex formation and higher wall shear stress (WSS) values compared to the Edwards valve, which may influence the risk of vascular damage and thrombosis.
  • This research could help predict negative flow phenomena post-implantation, aiding in the selection of more suitable valve designs for patients.
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Background: The ideal bifurcation stenting technique is not established, and data on the hemodynamic characteristics at stented bifurcations are limited.

Methods And Results: We used computational fluid dynamics analysis to assess hemodynamic parameters known affect the risk of restenosis and thrombosis at coronary bifurcations after the use of various single- and double-stenting techniques. We assessed the distributions and surface integrals of the time averaged wall shear stress (TAWSS), oscillatory shear index (OSI), and relative residence time (t(r)).

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Flow patterns may affect the potential of thrombus formation following plaque rupture. Computational fluid dynamics (CFD) were employed to assess hemodynamic conditions, and particularly flow recirculation and vortex formation in reconstructed arterial models associated with ST-elevation myocardial infraction (STEMI) or stable coronary stenosis (SCS) in the left anterior descending coronary artery (LAD). Results indicate that in the arterial models associated with STEMI, a 50% diameter stenosis immediately before or after a bifurcation creates a recirculation zone and vortex formation at the orifice of the bifurcation branch, for most of the cardiac cycle, thus allowing the creation of stagnating flow.

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This study aimed at investigating the effect of myocardial motion on pulsating blood flow distribution of the left anterior descending coronary artery in the presence of atheromatous stenosis. The moving 3D arterial tree geometry has been obtained from conventional x-ray angiograms obtained during the heart cycle and includes a number of major branches. The geometry reconstruction model has been validated against projection data from a virtual phantom arterial tree as well as with CT-based reconstruction data for the same patient investigated.

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Objective: To develop and implement a method for three-dimensional (3D) reconstruction of coronary arteries from conventional monoplane angiograms.

Background: 3D reconstruction of conventional coronary angiograms is a promising imaging modality for both diagnostic and interventional purposes.

Methods: Our method combines image enhancement, automatic edge detection, an iterative method to reconstruct the centerline of the artery and reconstruction of the diameter of the vessel by taking into consideration foreshortening effects.

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The detachment of liquid droplets from porous material surfaces used with proton exchange membrane (PEM) fuel cells under the influence of a cross-flowing air is investigated computationally and experimentally. CCD images taken on a purpose-built transparent fuel cell have revealed that the water produced within the PEM is forming droplets on the surface of the gas-diffusion layer. These droplets are swept away if the velocity of the flowing air is above a critical value for a given droplet size.

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