Angiotensin II receptor blockers (ARBs), like losartan, may help prevent symptoms of PTSD and enhance memory, though the exact brain mechanisms involved remain unclear.
A study with 40 anxious participants tested losartan against a placebo, observing brain activity during image encoding using functional MRI.
Results indicated that losartan improved processing in the parahippocampal gyrus but did not significantly affect memory recognition or overall hippocampal activation, suggesting ARBs may support visual processing related to memory input.