Publications by authors named "Theodoor D Witkamp"
Article Synopsis
- Delirium, a condition that can happen after surgery, may cause problems with thinking and lead to changes in the brain over time.
- The study looked at brain scans of elderly patients before and three months after major surgery, comparing them to a group of people who didn't have surgery.
- Results showed that patients who had delirium after surgery had a bigger decrease in brain volume, especially in a part called grey matter, compared to those who didn't have delirium.
Article Synopsis
- The study investigates how to differentiate between true progressive disease and treatment-induced effects in patients with high-grade gliomas using conventional MRI characteristics, highlighting the importance of accurate diagnosis.
- Data from 210 patients revealed specific MRI features and time to progression that are associated with higher odds of diagnosing progressive disease, such as radiation dose, marginal enhancement, and isointense ADC signals.
- The findings contribute to improving diagnostic models for assessing patient conditions post-treatment, underscoring the effectiveness of certain MRI characteristics in distinguishing between disease progression and treatment effects.
The relevance of intracranial vessel wall lesions detected with MRI is not fully established. In this study (trial identification number: NTR2119; www.trialregister.
View Article and Find Full Text PDFFrailty is a common syndrome in older individuals that is associated with poor cognitive outcome. The underlying brain correlates of frailty are unclear. The aim of this study was to investigate the association between frailty and MRI features of cerebral small vessel disease in a group of non-demented older individuals.
View Article and Find Full Text PDF