A comprehensive comparison between ISAC and ALEX multiplex test systems.

Objectives: Diagnosis of type I hypersensitivity is based on anamnesis, provocation as well as blood- and skin testing. Multiplex specific IgE (sIgE) testing enables determination of sIgE antibodies against multiple recombinant or purified natural allergen components. The aim of this study was to evaluate the performance of the novel ALEX (Allergy Explorer, ALEX test introduced on the market November 2019) multiplex platform and to compare it with the ImmunoCAP ISAC test system.