Publications by authors named "Theo Constant"

Article Synopsis
  • Oxidative stress contributes significantly to aging by damaging cells and leading to apoptosis, with telomere shortening being a key indicator of biological aging.
  • Hibernators, despite facing high levels of oxidative stress during their rewarming phase, exhibit surprisingly long lifespans, prompting an exploration of their unique adaptive mechanisms.
  • This study highlights how hibernating rodents manage oxidative stress through seasonal variations in telomere length and emphasizes the need to reconsider telomeres as aging markers in species with seasonal life strategies.
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Seasonal animal dormancy is widely interpreted as a physiological response for surviving energetic challenges during the harshest times of the year (the physiological constraint hypothesis). However, there are other mutually non-exclusive hypotheses to explain the timing of animal dormancy, that is, entry into and emergence from hibernation (i.e.

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Low mortality rate is often associated with slow life history, and so far, has mainly been assessed through examinations of specific adaptations and lifestyles that limit mortality risk. However, the organization of activity time budgets also needs to be considered, since some activities and the time afforded for performing them may expose animals to higher mortality risks such as increased predation and/or increased metabolic stress. We examined the extent of activity time budgets contribution to explaining variation in life history traits in mammals.

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