Publications by authors named "Theo Blaise"
Background: Plasmodium vivax relapses due to dormant liver hypnozoites can be prevented with primaquine. However, the dose must be adjusted in individuals with glucose-6-phosphate-dehydrogenase (G6PD) deficiency. In French Guiana, assessment of G6PD activity is typically delayed until day (D)14 to avoid the risk if misclassification.
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- French Guiana is a unique region notable for its rich biodiversity and diverse communities, yet it faces paradoxes such as high poverty rates with 50% of the population living below the poverty line.
- The territory experiences a mix of health challenges, including common infectious diseases like HIV and malaria, which require tailored medical approaches due to their unique local characteristics.
- European resources in French Guiana facilitate advanced diagnostic and treatment options, enhancing research opportunities despite the smaller population compared to surrounding countries, and enabling better management of both common and rare diseases.
Importance: Patients with scarred vocal folds, whether congenitally or after phonosurgery, often exhibit dysphonia that negatively affects daily life and is difficult to treat. The autologous adipose tissue-derived stromal vascular fraction (ADSVF) is a readily accessible source of cells with angiogenic, anti-inflammatory, immunomodulatory, and regenerative properties.
Objective: To evaluate the feasibility and tolerability of local injections of autologous ADSVF in patients with scarred vocal folds.