Melianone inhibits Secreted Aspartic Proteases (SAP), a Virulence Factor During Hyphal Formation in .

Background & Objective: Candida albicans (C.-P. Robin) Berkhout, the pathogenic yeasts' ability to transform from yeast to hyphal forms in the bloodstream is essential during systemic infections.

Effect of orientation of transcription of a gene in an inverted transferred DNA repeat on transcriptional gene silencing in rice transgenics-a case study.

We studied transgene silencing in two transgenic rice plants, OSM25 and COT-OSM4, which harboured two different types of right border (RB)-centered inverted transferred DNA (T-DNA) repeats (IRs). The T-DNA in OSM25 has three genes gus, OSM and hph, all under the transcriptional control of the Cauliflower mosaic virus 35S promoter (P35S). The gus gene, which is proximal to the RB, is in a convergent orientation of transcription in the IR.