Publications by authors named "Themis Macedo Pereira da Costa"
Prevalence of orofacial alterations in patients with sickle-cell disease: Systematic review and meta-analysis.
Themis Macedo Pereira da Costa Monikelly do Carmo Chagas Nascimento Mariela Peralta-Mamani Izabel Regina Fischer Rubira-Bullen José Luiz Cintra Junqueira
Oral Surg Oral Med Oral Pathol Oral Radiol
May 2023
Article Synopsis
- The study aimed to find out how common orofacial changes are in people with sickle-cell disease (SCD) and to compare these findings with those from the general population.
- A total of 28 studies were selected from 770 records, indicating significant issues like decreased bone density (57%), malocclusion (66%), and delayed tooth eruption (20%) in SCD patients.
- The research noted a high risk of bias due to small sample sizes and a lack of comparisons between SCD patients and healthy individuals regarding these orofacial alterations.