Publications by authors named "Thellamudhu Ganesan"
Scope: Increased fat consumption in industrialized countries has resulted in hepatic steatosis that upregulates atherogenic aspirant genes, leading to atherosclerosis and mortality. Although extensive studies have been carried out to elucidate the atheroprotective efficacy of epigallocatechin-3-gallate (EGCG), the effect of EGCG on hepatic steatosis has not been studied comprehensively. Hence, the current study was designed to find out the effect of EGCG on hepatic events that prelude atherosclerosis with special reference to macrophage infiltration.
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- - Oxidative stress plays a key role in kidney diseases by causing cellular damage through increased reactive oxygen species (ROS); this study examines the impact of homeopathic treatment on oxidative stress in kidney stone disease using rats as a model.
- - The research involves administering a homeopathic preparation from Berberis vulgaris and evaluating its effect on the renal antioxidant defense system and free radical activity markers in rat kidneys.
- - Results show that the homeopathic preparation significantly boosts the activity of enzymatic and nonenzymatic antioxidants, reduces markers of oxidative damage, and provides protective effects to the kidneys against oxidative stress.
Purpose: The study focuses on the anti-urolithiasis potential of ultra-diluted homeopathic potency of Berberis vulgaris (B. vulgaris) root bark, commonly used in homeopathic system to treat renal calculi.
Methodology: B.
Objectives: Oxidative stress is recognized as a key element responsible for the development of age-related pathologies. A declining endogenous defence system during senescence dictates the need for supplementation with exogenous antioxidants through diet. Hesperidin is a naturally occurring flavonone present in citrus fruits and has been shown to have many biological properties, including antioxidant activity.
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