An outbreak of hepatitis A in school children at Nakhon Si Thammarat, southern Thailand.

Hepatitis A antibody prevalence in Southeast Asia has markedly declined among children and adolescents. Therefore increasing a number of susceptible populations could result in an outbreak or epidemic. This paper reports an intensive study of an outbreak of hepatitis A in a primary school children during an endemic at Nakhon Si Thammarat, Southern Thailand.

Comparative results in detection of HCV antibodies by using a rapid HCV test, ELISA and immunoblot.

Viral hepatitis C is a major problem of post-transfusion hepatitis. The best measure for preventing hepatitis C infection in transfusion is blood donor screening. There are many methods for detecting hepatitis C virus antibodies.

Randomized, single-blind comparison of the immunogenicity and reactogenicity of 20 micrograms and 10 micrograms doses of hepatitis B vaccine in adolescents.

The study compares the effect of two different doses of a recombinant DNA hepatitis B vaccine (Engerix-B) administered to 320 healthy adolescents divided randomly into two equal groups, using the 0, 1 and 6 month's vaccination schedule. Initially the larger dose elicited protective levels of antibody in a greater proportion of subjects. The seroprotection rates were significantly higher at both months 1 (17.

Changing seroepidemiology of hepatitis A virus infection in Thailand.

Hepatitis A is an infectious disease commonly found in many developing countries. The infection usually is asymptomatic in children and only a small percentage has clinical hepatitis of varying severity. Hepatitis A infection becomes more symptomatic with increasing age.

Seroepidemiology of antibody to hepatitis A in the rural eastern part of Thailand.

Hepatitis A is a disease commonly found in Thai children. However, there are very few reports on the age specific prevalence in Thailand. We studied the hapatitis A virus (HAV) antibody titer in a population in the rural eastern part of Thailand, using an antiHAV ELISA test (Abbott Laboratories, North Chicago Ill).