Clinical Impact of Pelvic Lymph Node Status in Locally Advanced Cervical Cancer Patients Treated by Concurrent Chemoradiation Therapy.

Objective: To explore the treatment outcomes of locally advanced cervical cancer (LACC) patients with pelvic lymph node enlargement (PLNE) or stage IIIC1 when compared with no PLNE and unknown PLN status (UNK).

Materials And Methods: Retrospective cohort study was designed by matching with the ratio of 1:4:4 for patients with PLNE, no PLNE and UNK between 2003 and 2017. The main factor which was used to match was clinical staging.

Inappropriate gestational weight gain among teenage pregnancies: prevalence and pregnancy outcomes.

Objective: To study the prevalence and pregnancy outcomes of inappropriate gestational weight gain (GWG) among teenage pregnant women.

Methods: A retrospective descriptive study was conducted on 2,165 teenage pregnant women who attended our antenatal clinic between January 2007 and August 2015. Adverse pregnancy outcomes, including maternal and neonatal outcomes of women with inappropriate GWG, including underweight and overweight, were studied and compared with those of women with appropriate GWG.

Prevalence and Associated Factors of Abnormal Cervical Cytology and HighRisk HPV DNA among Bangkok Metropolitan Women.

Background: Many strategies are required for cervical cancer reduction e.g. provision of education cautious sexual behavior, HPV vaccination, and early detection of preinvasive cervical lesions and invasive cancer.

Uterine Sarcoma: Clinical Presentation, Treatment and Survival Outcomes in Thailand.

Background: Uterine sarcoma is a group of rare gynecologic tumors with various natures, and different lines of treatment. Most have a poor treatment outcome. This study targeted clinical characteristics, treatment, overall survival (OS), progression-free survival (PFS), and prognostic factors in uterine sarcoma patients in one tertiary center for cancer care.

Knowledge, Attitudes and Behavior of Bangkok Metropolitan Women Regarding Cervical Cancer Screening.

Purpose: To assess knowledge, attitudes and cervical cancer screening behavior of Bangkok Metropolitan women.

Materials And Methods: Thai women, aged 25-to-65 years old, having lived in Bangkok for 5 years or more were invited to participate in the study. After signing informed consent, all women were asked to complete a self-questionnaire (Thai language) with literate assistance if needed.

Patterns of adjuvant therapy for endometrial cancer: single institutional experience in Thailand.

Aim: The aim of this study was to evaluate the use of adjuvant therapy and treatment outcomes in patients with endometrial cancer (EMC).

Methods: Patients with EMC treated in the institution were identified. Data collected were age, stage of disease, histopathology, and adjuvant therapy.

Treatment outcomes of paclitaxel for refractory or recurrent epithelial ovarian cancer patients in Thailand.

Background: To study the response rate, toxicity profiles, and survival of refractory or recurrent epithelial ovarian cancer (EOC) patients treated with paclitaxel.

Materials And Methods: Patients with refractory or recurrent EOC who were treated with paclitaxel between January 2002 and December 2011 at the Department of Obstetrics and Gynecology, Faculty of Medicine, Vajira Hospital were identified. Clinicopathological features of the patients including detailed data of paclitaxel treatment were collected.

Platelet to lymphocyte ratio as a prognostic factor for epithelial ovarian cancer.

Objective: To determine whether preoperative platelets to lymphocyte ratio (PLR) could predict disease stage, surgical outcome, and survival in patients with epithelial ovarian cancer (EOC).

Methods: Medical records of EOC patients who had surgery between January 2004 and December 2010 were reviewed. Clinicopathological and complete blood count data were collected.

Role of neutrophil to lymphocyte ratio as a prognostic indicator for epithelial ovarian cancer.

Objective: To determine whether level of preoperative peripheral blood neutrophil to lymphocyte ratio (NLR) was a prognostic indicator for epithelial ovarian cancer (EOC) patient. The present study further aimed to evaluate the impact of the change of preoperative/postoperative NLR on the survival.

Material And Method: Medical records of the patients undergoing an operation for EOC in Vajira Hospital between January 1, 2004 and December 31, 2009 were reviewed.

Clinicopathological features including hormonal receptor expression and survival in young endometrial cancer patients: a case control study.

Objective: To compare clinicopathological features, including hormonal receptor expression and survival, in young Thai endometrial carcinoma (EMC) patients with older patients.

Methods: Young EMC patients aged ≤45 years, treated in the institution from 1992 to 2008, were identified as cases. Controls included EMC patients aged >45 years who had an operation on the nearest dates to the cases.

Endometrial cancer in Thai women: clinico-pathological presentation and survival.

Objective: To assess the characteristic features, treatment, survival, and prognostic factors of Thai endometrial cancer (EMC) patients.

Methods: Clinico-pathological data of EMC patients who were treated in the institution from 1992 to 2008 were collected. Survival rates and prognostic factors were studied.

Expression of ER, PR, and Her-2/neu in endometrial cancer: a clinicopathological study.

Objective: To determine any association between expression of estrogen receptor (ER), progesterone receptor (PR), and Her-2/neu and clinicopathological features, including survival, of endometrial carcinoma (EMC) patients.

Methods: Samples of formalin-fixed, paraffin-embedded tissue of 108 patients with EMC treated at our institution between January 1994 and December 2007 were immunohistochemically studied.

Results: ER, PR, and Her-2/neu expression were positive in 59.

Expression of Cyclooxygenase-1 and 2 in Epithelial Ovarian Cancer: A Clinicopathologic Study.

Background: To examine the rate and degree of expression of Cyclooxygenase-1 (COX-1) and Cyclooxygenase-2 (COX-2) in epithelial ovarian cancer (EOC) and associated with clinicopathological factors and survival.

Methods: EOC patients being treated in our institute with available pathological tissue sections during 1996-2003 were identified. Immunohistochemical staining with antibody to COX-1 and COX-2 were studied.

Malignant ovarian germ cell tumors: clinico-pathological presentation and survival outcomes.

Objective: To evaluate clinico-pathological features, treatment, survival, and prognostic factors of patients with malignant ovarian germ cell tumors.

Design: Descriptive study.

Setting: Bangkok Metropolitan Administration Medical College and Vajira Hospital and Prince of Songkla University.

Oral etoposide for refractory or recurrent epithelial ovarian cancer.

Objective: To study the response rate (RR), toxicity, progression-free survival (PFS), and overall survival (OS) of the patients with recurrent or refractory epithelial ovarian cancer (EOC), who had oral etoposide at dosage of 75 mg/day.

Material And Method: Patients with recurrent or refractory EOC who were treated with oral etoposide between January 1998 and December 2007 were identified from the Archive of the Gynecologic Oncology Unit of the institution. Clinical and pathological data were reviewed.

Prevalence of high grade squamous intraepithelial lesions (HSIL) and invasive cervical cancer in patients with atypical squamous cells of undetermined significance (ASCUS) from cervical pap smears.

To determine the prevalence and factors associated with histologic diagnoses of High Grade Squamous Intraepithelial Lesions (HSIL) or invasive cervical cancer in women with a cytologic diagnosis of atypical squamous cells of undertermined significance (ASCUS), medical records of women with an ASCUS Pap smear from January 2003 to December 2006 were reviewed. Of 287 women with ASCUS Pap smears in whom data were available, 189 were annotated with "favoring a premalignant or malignant process", 74 with "favoring reactive", and 24 with "not otherwise specified". The prevalences of HSIL and invasive cervical cancer were 9.

Prevalence of high grade squamous intraepithelial lesion (HSIL) and invasive cervical cancer in patients with low grade squamous intraepithelial lesion (LSIL) at cervical pap smear.

Objective: To assess the prevalence and factors associated with a histologic diagnosis of high grade squamous intraepithelial lesion (HSIL) and invasive cervical cancer in patients with low grade squamous intraepithelial lesion (LSIL) cervical pap smear findings.

Methods: Medical records (including cytology reports, colposcopic impression, and pathologic results from cervical biopsy, endocervical curetting, cervical conization or hysterectomy) of 226 women with LSIL from conventional cervical pap smears during January 2001 to December 2005, who subsequently underwent colposcopic evaluation at our institution, were reviewed.

Results: Mean age of the patients was 39.

Results of laparoscopic pelvic and/or para-aortic lymphadenectomy in gynecologic oncology patients in Bangkok Metropolitan Administration Medical College and Vajira Hospital.

Objective: To determine the results of laparoscopic lymphadenectomy in gynecologic oncology patients.

Material And Method: Medical records of 31 gynecologic oncology patients who underwent laparoscopic lymphadenectomy between November 1, 2004 and February 28, 2007 were retrospectively reviewed.

Results: The median age of the study population was 47 years (range 24-77 years).

Tumor persistence in high grade squamous intraepithelial lesion patients with positive surgical margin post loop electrosurgical excision procedure.

Objective: To determine the rates of persistent and recurrent tumors in patients with High Grade Squamous Intraepithelial Lesion (HSIL) who had positive surgical margin from Loop Electrosurgical Excision Procedure (LEEP).

Material And Method: Clinical and pathological data of all women who underwent LEEP procedures and revealed HSIL lesions with positive surgical margin between July 1997 and December 2004 were recorded.

Results: Histologic diagnoses of HSIL with positive surgical margin were found in 95 cases during the study period.