Publications by authors named "Thaon I"

Introduction: Questions concerning under-reporting of occupational diseases (OD) linked to asbestos exposure are regularly voiced in France. Monitoring of the French multicenter Asbestos-Related Disease Cohort (ARDCO), which ensures post-occupational medical surveillance of subjects having been exposed to asbestos, provides information on (1) the medico-legal steps taken following screening by computed tomography (CT) for benign thoracic diseases, and (2) recognition of OD as a causal factor in malignant diseases.

Methods: OD recognition - and possible compensation - was analyzed in July 2021 among 13,289 volunteers in the cohort recruited between 2003 and 2005.

View Article and Find Full Text PDF
Article Synopsis
  • This study aimed to explore how different aspects of asbestos exposure relate to pleural plaques (PP) in retired workers in France.
  • A large screening program conducted from 2003 to 2016 involved 5,392 participants, with HRCT scans and detailed evaluations of their work history to gauge their asbestos exposure levels.
  • The findings revealed complex, non-linear relationships where the risk of PP increased with higher cumulative asbestos exposure and longer periods since first exposure, while the odds decreased with longer times since last exposure.
View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the health-related quality of life (HRQoL) of retired men exposed to asbestos, focusing on how perceived risks and respiratory symptoms impact their well-being.
  • - Researchers analyzed questionnaires from 1,266 retired workers, finding that a higher perceived risk of asbestos exposure correlated with lower scores in both physical and mental health components.
  • - The presence of respiratory symptoms was significantly linked to decreased HRQoL, while expert assessments of asbestos exposure didn't show a direct impact on health outcomes.
View Article and Find Full Text PDF

Objectives: Studies on the impact of long COVID on work capacity are increasing but are difficult to locate in bibliographic databases, due to the heterogeneity of the terms used to describe this new condition and its consequences. This study aims to report on the effectiveness of different search strategies to find studies on the impact of long COVID on work participation in PubMed and to create validated search strings.

Methods: We searched PubMed for articles published on Long COVID and including information about work.

View Article and Find Full Text PDF

Purpose: This study aims to report on the effectiveness of various search strategies and keywords to find studies on work-related psychosocial risk factors (PRF) in the PubMed bibliographic database.

Methods: We first selected by hand-searching 191articles published on PRF and indexed in PubMed. We extracted 30 relevant MeSH terms and 38 additional textwords.

View Article and Find Full Text PDF
Article Synopsis
  • Previous studies on the link between refractory ceramic fibers (RCFs), mineral wool fibers (MWFs), and pleural plaques have been inconsistent, often relying on chest radiographs, which are not very accurate.
  • This research investigates whether cumulative exposure to RCFs, MWFs, and silica increases the risk of pleural plaques, and how this risk interacts with co-exposure to asbestos.
  • Among 5,457 subjects screened with CT scans, the study found significant dose-response relationships, with higher cumulative exposure to RCFs and MWFs leading to an increased risk of pleural plaques, especially in individuals also exposed to asbestos.
View Article and Find Full Text PDF

: The National Lung Screening Trial (NLST) and NELSON study opened the debate on the relevance of lung cancer (LC) screening in subjects exposed to occupational respiratory carcinogens. This analysis reported the incremental cost-effectiveness ratios (ICER) of an organized LC screening program for an asbestos-exposed population. Using Markov modelization, individuals with asbestos exposure were either monitored without intervention or annual low-dose thoracic computed-tomography (LDTCT) scan LC screening.

View Article and Find Full Text PDF

Background: Occupational asbestos exposure is associated with pleural plaques (PP), a benign disease often seen as a marker of past exposure to asbestos and lung cancer. The association between these two diseases has not been formally proved, the aim of this study was to evaluate this association in the asbestos-related disease cohort (ARDCO) cohort.

Methods: ARDCO is a French multicentric cohort including workers formerly occupationally exposed to asbestos from 2003 to 2005.

View Article and Find Full Text PDF

Objectives: The aim of this study was to analyse, within a French cohort of workers previously occupationally exposed to asbestos, incidence and mortality from various sites of head and neck cancers (larynx excluded) and to examine the potential link of these cancers with pleural plaques.

Methods: A 10-year follow-up study was conducted in the 13 481 male subjects included in the cohort between October 2003 and December 2005. Asbestos exposure was assessed by industrial hygienist analysis of a standardised questionnaire.

View Article and Find Full Text PDF

Objective: This study aimed to develop and validate an automated artificial intelligence (AI)-driven quantification of pleural plaques in a population of retired workers previously occupationally exposed to asbestos.

Methods: CT scans of former workers previously occupationally exposed to asbestos who participated in the multicenter APEXS (Asbestos PostExposure Survey) study were collected retrospectively between 2010 and 2017 during the second and the third rounds of the survey. A hundred and forty-one participants with pleural plaques identified by expert radiologists at the 2nd and the 3rd CT screenings were included.

View Article and Find Full Text PDF

Objective: the aim of this study was to evaluate the association between interstitial lung abnormalities, asbestos exposure and age in a population of retired workers previously occupationally exposed to asbestos.

Methods: previously occupationally exposed former workers to asbestos eligible for a survey conducted between 2003 and 2005 in four regions of France, underwent chest CT examinations and pulmonary function testing. Industrial hygienists evaluated asbestos exposure and calculated for each subject a cumulative exposure index (CEI) to asbestos.

View Article and Find Full Text PDF

Introduction: Given the extent of workaholism identified in the literature, it seems essential to consider effective preventive measures. The purpose of this article is to summarize literature data on possible collective and individual preventive measures against workaholism, especially in occupational medicine.

Method: We conducted a systematic literature review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

View Article and Find Full Text PDF

Work-related asthma (WRA) is a very frequent condition in the occupational setting, and refers either to asthma induced (occupational asthma, OA) or worsened (work-exacerbated asthma, WEA) by exposure to allergens (or other sensitizing agents) or to irritant agents at work. Diagnosis of WRA is frequently missed and should take into account clinical features and objective evaluation of lung function. The aim of this overview on pulmonary function testing in the field of WRA is to summarize the different available tests that should be considered in order to accurately diagnose WRA.

View Article and Find Full Text PDF

Introduction: In France, long-term follow-up after occupational exposure to asbestos is recommended. This study looked at the psychological consequences in the longer term following a CT-scan, in particular the impact of having received compensation for an occupational disease.

Methods: As part of an asbestos post-exposure survey study (APExS), volunteers from Normandy were asked to complete self-assessment questionnaires about their psychological condition at different points during follow-up, including a psychological questionnaire before, then 6 months, and finally 18 to 24 months after their chest CT-scan.

View Article and Find Full Text PDF

Introduction: Playing a wind instrument is an increasingly reported cause of hypersensitivity pneumonitis. However, current knowledge about contamination of wind instruments by fungi and specific fungal sensitization is scarce. Therefore, we aimed: (i) to assess the current prevalence and type of fungal contamination of wind instruments, (ii) to identify potential risk factors associated with instrument contamination, and (iii) to evaluate the prevalence of sensitization to these fungi among musicians.

View Article and Find Full Text PDF

Objective: Most research on night and shift work focuses on employee health in large companies, primarily in the healthcare and transportation sectors. However, many night workers work on their own or in small businesses related to services or food. This survey focuses on sleep habits and disorders concerning night work in pastry production and sales.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the link between asbestos exposure and esophageal cancer among workers in the ARDCo Program.
  • A 10-year follow-up of 14,515 male participants was conducted to assess the incidence and mortality rates of esophageal cancer after their asbestos exposure ended.
  • The results showed a significant connection, revealing that higher cumulative asbestos exposure increased both the risk of developing esophageal cancer and the likelihood of dying from it.
View Article and Find Full Text PDF

Background: The relationships between asbestos exposure and colorectal cancer remain controversial.

Objectives: We examined the association between asbestos exposure and colorectal cancer incidence.

Methods: Volunteer retired workers previously exposed to asbestos were invited to participate in the French ARDCo screening program between 2003 and 2005.

View Article and Find Full Text PDF

Background: Asbestos is known to be an independent risk factor for lung and pleural cancers. However, to date, little attention has been paid to the psychological effects of asbestos exposure among exposed subjects. The objectives of this study were to estimate the prevalence of anxious and depressive symptoms among >2000 French participants of the Asbestos-Related Diseases Cohort (ARDCO), 6 years after their inclusion, to identify the risk factors associated with those anxious and depressive symptoms and to evaluate the impact of the asbestos-risk perception.

View Article and Find Full Text PDF
Article Synopsis
  • Dairy farming is linked to a high prevalence of chronic obstructive pulmonary disease (COPD), but modern farm practices may reduce exposure to COPD-causing agents.
  • A study of 575 male dairy farmers in France found a COPD prevalence of 12.0% using GOLD criteria and 5.6% using the lower limit of normal (LLN) definition.
  • Factors like tobacco smoking and traditional farming characteristics were associated with increased COPD prevalence, suggesting that modern farming practices may have a beneficial impact on respiratory health.
View Article and Find Full Text PDF

Background: Argan is used worldwide in numerous cosmetic products, as this fruit is supposed to have many beneficial properties on health. New cases of allergy can be expected with the growing use of argan. We investigated all workers (9) employed by a cosmetic factory and exposed to argan powder to identify possible allergies related to exposure to argan powder.

View Article and Find Full Text PDF

Background: Argan is now used worldwide in numerous cosmetic products. Nine workers from a cosmetic factory were examined in our occupational medicine department, following the diagnosis of a case of hypersensitivity pneumonitis (HP) related to handling of argan cakes.

Methods: Operators were exposed to three forms of argan (crude granulates, powder or liquid) depending on the step of the process.

View Article and Find Full Text PDF

Background: Fractional exhaled nitric oxide (FENO) levels are increasingly being used in the diagnosis and management of asthma. However, this indicator has rarely been used to detect occupational asthma.

Objective: To examine non-invasive methods to estimate airway inflammation.

View Article and Find Full Text PDF