Assessment of early goal-directed therapy guideline adherence: Balancing clinical importance and feasibility.

Background: Assessing adherence to Early goal-directed therapy (EGDT) is challenging and might account for the negative findings and generalisability of the major trials to a real-life setting. This study was aimed (1) to extract key components of pediatric EGDT guidelines potentially becoming adherence criteria; (2) to classify adherence criteria into complete, clinically important, and feasible; and (3) to compare percent adherence to selected guidelines using the three approaches.

Methods: This study started with review of existing evidence to extract key components of pediatric EGDT guidelines.