Publications by authors named "Thanh Tan Vo"
The role of parvalbumin (PV) interneurons in vascular control is poorly understood. Here, we investigated the hemodynamic responses elicited by optogenetic stimulation of PV interneurons using electrophysiology, functional magnetic resonance imaging (fMRI), wide-field optical imaging (OIS), and pharmacological applications. As a control, forepaw stimulation was used.
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- fMRI combined with optogenetics allows researchers to map brain networks effectively by enabling precise neural manipulation in real-time.
- By using a digital micromirror device, scientists can create customizable light patterns for stimulating specific brain areas in mice while conducting imaging.
- This technique reveals that brain connectivity is influenced by the type of anesthetics used and opens new avenues for studying how brain functions change dynamically in individual animals.
The BOLD fMRI response in the cortex is often assumed to reflect changes in excitatory neural activity. However, the contribution of inhibitory neurons to BOLD fMRI is unclear. Here, the role of inhibitory and excitatory activity was examined using multimodal approaches: electrophysiological recording, 15.
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