Publications by authors named "Thanh P Nguyen"

To meet various industrial requirements such as ease of motion, scalability, and cost efficiency, it is necessary to innovate the design of robotic platforms. In this research, a novel approach, from mechanical design to control implementation, is introduced for launching a robotic platform using a parallelogram mechanism. First, a reverse engineering process is applied, progressing from kinematics to dynamics.

View Article and Find Full Text PDF

The rapid and widespread increase in pharmaceutical micropollutants (PMPs) poses a significant and immediate threat to ecosystems and human health globally. With the demand for clean water becoming increasingly critical, particularly amid escalating global water scarcity challenges, there is an urgent need for innovative approaches. Among the potential solutions, metal oxide photocatalysts such as titanium dioxide-based (TiB) and zinc oxide-based (ZnB) have garnered attention due to their cost-effectiveness, efficient photodegradation capabilities, and inherent stability.

View Article and Find Full Text PDF
Article Synopsis
  • * A study in Lam Dong province analyzes water distribution and agricultural water demand under two scenarios: the current condition in 2020 and projected impacts of climate change by 2025 using advanced modeling tools.
  • * The research finds that under drier conditions, water demand for crops decreases significantly as drought severity increases, emphasizing the need for effective adaptation strategies to manage irrigation and sustain agriculture in the region.
View Article and Find Full Text PDF
Article Synopsis
  • The paper introduces CORING, a new method for pruning filters in neural networks that focuses on efficient tensor decomposition, moving away from traditional vectorized techniques.
  • CORING utilizes the HOSVD tensor decomposition to maintain the multidimensional quality of filters while significantly lowering computational complexity.
  • Experiments show CORING surpasses existing methods in reducing MACs (Multiply-Accumulate operations) and parameters, while improving validation accuracy across various vision tasks, supported by an in-depth ablation study and qualitative results.
View Article and Find Full Text PDF

This study represents an innovative approach to construct multi-functional nanoplatforms for cancer diagnosis and therapy by combining hyaluronic acid (HA) with iron-platinum nanoparticles (FePt NPs). These HA-coated FePt NPs, referred to as FePt@HA NPs, demonstrated remarkable biocompatibility, high absorption, and excellent light-to-heat conversion properties in the near-infrared (NIR) region, making them ideal candidates for photothermal therapy (PTT). In vitro studies revealed their effective cancer cell eradication under NIR laser irradiation, while in vivo experiments on mice showcased their superior heating capabilities.

View Article and Find Full Text PDF
Article Synopsis
  • Epithelia require mechanical resistance to maintain tissue integrity, with tight junctions (TJs) playing a significant but not fully understood role.
  • Research shows that cells lacking TJs due to missing proteins claudins and JAM-A experience junction fractures when stretched.
  • Further studies indicate that actin organization and the protein CAR are essential for maintaining the integrity of apical junctions in epithelial cells.
View Article and Find Full Text PDF
Article Synopsis
  • NORTON is a new network compression method that combines tensor decompositions and pruning to improve model efficiency and performance.
  • It features a unique filter decomposition process that maintains the complex properties of the network weights while allowing for more detailed analysis.
  • Extensive testing shows that NORTON outperforms existing state-of-the-art techniques in both accuracy and complexity, with code available for further research.
View Article and Find Full Text PDF
Article Synopsis
  • Antimicrobial photodynamic therapy (APDT) utilizes light-activated compounds called photosensitizers to combat antibiotic-resistant bacteria.
  • This study tested various plant extracts as photosensitizers against gram-negative (Pseudomonas aeruginosa) and gram-positive (Staphylococcus aureus) bacteria, showing them to be effective in generating singlet oxygen for bacterial inactivation.
  • The results indicated that exposing P. aeruginosa to 405 nm light produced a significant reduction in bacterial counts, while S. aureus showed a similar effectiveness across all tested light wavelengths and doses.
View Article and Find Full Text PDF

Objectives: Quality of surgery has recently become an essential topic in the prognosis of colon cancer. Complete mesocolic excision for colon cancer has recently gained popularity with high-quality surgery. Patient specimens after complete mesocolic excision with central vessel ligation procedures have an integrity of the mesocolon and the yield of three fields of lymph node harvest.

View Article and Find Full Text PDF
Article Synopsis
  • - The study developed non-toxic quantum dots (QDs) using a starch paste stabilizer, revealing improved compatibility with antibodies due to the -CH-OH group in the starch.
  • - Different concentrations of manganese-doped ZnS in the QDs were tested, finding that a 3% Mn ratio yielded the best luminescence and quantum yield, enhancing fluorescence intensity compared to other formulations.
  • - The incorporation of protein A and EDC bridging technology demonstrated that the ZnSe/ZnS:3%Mn/ZnS-starch QDs exhibited strong signals and sensitivity, while being non-toxic to harmful bacteria like E. coli and MRSA.
View Article and Find Full Text PDF

Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) is a rare type of gastric carcinoma with controversial diagnosis and treatment. Recent data implies that deficiency mismatch repair proteins inducing microsatellite instability are considered one of the potential drivers of this disease. Hence, we report a stomach MiNEN with MMR protein loss.

View Article and Find Full Text PDF
Article Synopsis
  • Recent advancements in nanomaterials, specifically hydroxyapatite (HAp) doped with rare-earth elements like Yb and Gd, have shown promise for bioimaging applications due to improved bioactivity and imaging properties.
  • The synthesis of Yb-Gd-HAp nanoparticles involved a wet precipitation method, followed by characterizing them for crystal structure, functional groups, and surface area, alongside the development of an imaging contrast agent by conjugating with IR783 dye and folic acid.
  • In vitro studies confirmed the biocompatibility of the nanoparticles, and photodynamic therapy was tested on MDA-MB-231 breast cancer cells, demonstrating effective photosensitizing properties and reactive oxygen species generation.
View Article and Find Full Text PDF

Introduction: Infection with is a recognized cause of severe malaria including deaths. The exact burden and patterns of severe monoinfections is however still not well quantified, especially in endemic regions. We examined the magnitude and patterns of severe malaria caused by monoinfections of and associated predictors among patients admitted to a tertiary care center for malaria in Vietnam.

View Article and Find Full Text PDF

Polymer-based micro-optical components are very important for applications in optical communication. In this study, we theoretically investigated the coupling of polymeric waveguide and microring structures and experimentally demonstrated an efficient fabrication method to realize these structures on demand. First, the structures were designed and simulated using the FDTD method.

View Article and Find Full Text PDF

Reconstructing the ancestral state of a group of species helps answer many important questions in evolutionary biology. Therefore, it is crucial to understand when we can estimate the ancestral state accurately. Previous works provide a necessary and sufficient condition, called the big bang condition, for the existence of an accurate reconstruction method under discrete trait evolution models and the Brownian motion model.

View Article and Find Full Text PDF
Article Synopsis
  • Targeted radionuclide therapy (TRT) and immunotherapy are emerging cancer treatments, with research focused on their potential combinations for enhanced effectiveness.
  • TRT offers the advantage of treating multiple disease sites through intravenous administration, making it particularly useful in cases of metastatic cancer.
  • While preclinical studies show promise for combining TRT with immune checkpoint blockade, clinical results have been inconsistent, leading to ongoing trials to better understand their interactions and clinical applications.
View Article and Find Full Text PDF
Article Synopsis
  • Claudin-based tight junctions (TJs) are crucial for cell-cell adhesion in epithelial cells, typically found at the apical region.
  • The study investigates the role of scaffolding proteins ZO-1 and ZO-2 in the positioning of TJs by using a mutant form of claudin-3 that does not bind to these proteins.
  • Results show that this mutant claudin-3 can still localize and form functional TJs, indicating that the interaction with ZO proteins is not essential for forming TJs at cell contacts.
View Article and Find Full Text PDF

In this study, we report an advanced fabrication technique to develop a miniature focused needle transducer. Two different types of high-frequency (100 MHz) transducers were fabricated using the lead magnesium niobate-lead titanate (PMN-0.3PT) and lithium niobate (LiNbO) single crystals.

View Article and Find Full Text PDF

Purpose: This in-situ-study investigated if rinsing the oral cavity with a calcium containing solution or a fluoride containing mouthwash immediately before an erosive attack leads to reduced enamel softening.

Materials And Methods: Bovine enamel samples (n = 240) with measured baseline surface microhardness (KHN) were assigned to five series (S1-5). Twelve participants carried out each series as follows: Four enamel samples of the associated test series were placed in an intraoral appliance and carried in each participants' mouth.

View Article and Find Full Text PDF

Widespread seafloor methane venting has been reported in many regions of the world oceans in the past decade. Identifying and quantifying where and how much methane is being released into the ocean remains a major challenge and a critical gap in assessing the global carbon budget and predicting future climate [C. Ruppel, J.

View Article and Find Full Text PDF

Background: Dengue viruses (DENV) can be transmitted from an adult female Aedes aegypti mosquito through the germ line to the progeny; however, there is uncertainty if this occurs at a frequency that is epidemiologically significant. We measured vertical transmission of DENV from field-reared Ae. aegypti to their F1 progeny after feeding upon blood from dengue patients.

View Article and Find Full Text PDF

In this study, a photoacoustic microscopy (PAM) system based on a multifocal point (MFP) transducer was fabricated to produce a large depth-of-field tissue image. The customized MFP transducer has seven focal points, distributed along with the transducer's axis, fabricated by separate spherically-focused surfaces. These surfaces generate distinct focal zones that are overlapped to extend the depth-of-field.

View Article and Find Full Text PDF
Article Synopsis
  • Tight junctions (TJs) are crucial for maintaining the epithelial barrier and regulating cell polarity, though their exact role remains debated.
  • Claudins and cytoplasmic proteins ZO-1 and ZO-2 are key components of TJs, with ZO proteins essential for TJ structure and epithelial barrier function while claudins contribute to electrolyte permeability.
  • The study found that claudins help form membrane connections and maintain macromolecule permeability, while ZO-deficient cells showed disorganized polarity, indicating that claudins and JAM-A work together to coordinate TJ formation and epithelial cell orientation.
View Article and Find Full Text PDF

Photothermal therapy (PTT) using chitosan/fucoidan multilayer coating of gold nanorods (CS/F-GNRs) has emerged as an alternative strategy for cancer therapy. In this study, biocompatible CS/F-GNRs were synthesized as a new generation of photothermal therapeutic agents for in vivo cancer treatments owing to their good biocompatibility, photostability, and strong absorption in the near-infrared (NIR) region. The CS/F-GNRs showed a good size distribution (51.

View Article and Find Full Text PDF

The present study illustrates the design, fabrication, and evaluation of a novel multifocal point (MFP) transducer based on polyvinylidene fluoride (PVDF) film for high-frequency ultrasound application. The fabricated MFP surface was press-focused using a computer numerical control (CNC) machining tool-customized multi-spherical pattern object. The multi-spherical pattern has five spherical surfaces with equal area and connected continuously to have the same energy level at focal points.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session0lvpkf2hnai8ftoat1nkstojopuk9elc): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once