To meet various industrial requirements such as ease of motion, scalability, and cost efficiency, it is necessary to innovate the design of robotic platforms. In this research, a novel approach, from mechanical design to control implementation, is introduced for launching a robotic platform using a parallelogram mechanism. First, a reverse engineering process is applied, progressing from kinematics to dynamics.
View Article and Find Full Text PDFThe rapid and widespread increase in pharmaceutical micropollutants (PMPs) poses a significant and immediate threat to ecosystems and human health globally. With the demand for clean water becoming increasingly critical, particularly amid escalating global water scarcity challenges, there is an urgent need for innovative approaches. Among the potential solutions, metal oxide photocatalysts such as titanium dioxide-based (TiB) and zinc oxide-based (ZnB) have garnered attention due to their cost-effectiveness, efficient photodegradation capabilities, and inherent stability.
View Article and Find Full Text PDFThis study represents an innovative approach to construct multi-functional nanoplatforms for cancer diagnosis and therapy by combining hyaluronic acid (HA) with iron-platinum nanoparticles (FePt NPs). These HA-coated FePt NPs, referred to as FePt@HA NPs, demonstrated remarkable biocompatibility, high absorption, and excellent light-to-heat conversion properties in the near-infrared (NIR) region, making them ideal candidates for photothermal therapy (PTT). In vitro studies revealed their effective cancer cell eradication under NIR laser irradiation, while in vivo experiments on mice showcased their superior heating capabilities.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
March 2024
SAGE Open Med
March 2024
Objectives: Quality of surgery has recently become an essential topic in the prognosis of colon cancer. Complete mesocolic excision for colon cancer has recently gained popularity with high-quality surgery. Patient specimens after complete mesocolic excision with central vessel ligation procedures have an integrity of the mesocolon and the yield of three fields of lymph node harvest.
View Article and Find Full Text PDFMixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) is a rare type of gastric carcinoma with controversial diagnosis and treatment. Recent data implies that deficiency mismatch repair proteins inducing microsatellite instability are considered one of the potential drivers of this disease. Hence, we report a stomach MiNEN with MMR protein loss.
View Article and Find Full Text PDFIntroduction: Infection with is a recognized cause of severe malaria including deaths. The exact burden and patterns of severe monoinfections is however still not well quantified, especially in endemic regions. We examined the magnitude and patterns of severe malaria caused by monoinfections of and associated predictors among patients admitted to a tertiary care center for malaria in Vietnam.
View Article and Find Full Text PDFPolymer-based micro-optical components are very important for applications in optical communication. In this study, we theoretically investigated the coupling of polymeric waveguide and microring structures and experimentally demonstrated an efficient fabrication method to realize these structures on demand. First, the structures were designed and simulated using the FDTD method.
View Article and Find Full Text PDFReconstructing the ancestral state of a group of species helps answer many important questions in evolutionary biology. Therefore, it is crucial to understand when we can estimate the ancestral state accurately. Previous works provide a necessary and sufficient condition, called the big bang condition, for the existence of an accurate reconstruction method under discrete trait evolution models and the Brownian motion model.
View Article and Find Full Text PDFIn this study, we report an advanced fabrication technique to develop a miniature focused needle transducer. Two different types of high-frequency (100 MHz) transducers were fabricated using the lead magnesium niobate-lead titanate (PMN-0.3PT) and lithium niobate (LiNbO) single crystals.
View Article and Find Full Text PDFPurpose: This in-situ-study investigated if rinsing the oral cavity with a calcium containing solution or a fluoride containing mouthwash immediately before an erosive attack leads to reduced enamel softening.
Materials And Methods: Bovine enamel samples (n = 240) with measured baseline surface microhardness (KHN) were assigned to five series (S1-5). Twelve participants carried out each series as follows: Four enamel samples of the associated test series were placed in an intraoral appliance and carried in each participants' mouth.
Widespread seafloor methane venting has been reported in many regions of the world oceans in the past decade. Identifying and quantifying where and how much methane is being released into the ocean remains a major challenge and a critical gap in assessing the global carbon budget and predicting future climate [C. Ruppel, J.
View Article and Find Full Text PDFParasit Vectors
September 2020
Background: Dengue viruses (DENV) can be transmitted from an adult female Aedes aegypti mosquito through the germ line to the progeny; however, there is uncertainty if this occurs at a frequency that is epidemiologically significant. We measured vertical transmission of DENV from field-reared Ae. aegypti to their F1 progeny after feeding upon blood from dengue patients.
View Article and Find Full Text PDFIn this study, a photoacoustic microscopy (PAM) system based on a multifocal point (MFP) transducer was fabricated to produce a large depth-of-field tissue image. The customized MFP transducer has seven focal points, distributed along with the transducer's axis, fabricated by separate spherically-focused surfaces. These surfaces generate distinct focal zones that are overlapped to extend the depth-of-field.
View Article and Find Full Text PDFPhotothermal therapy (PTT) using chitosan/fucoidan multilayer coating of gold nanorods (CS/F-GNRs) has emerged as an alternative strategy for cancer therapy. In this study, biocompatible CS/F-GNRs were synthesized as a new generation of photothermal therapeutic agents for in vivo cancer treatments owing to their good biocompatibility, photostability, and strong absorption in the near-infrared (NIR) region. The CS/F-GNRs showed a good size distribution (51.
View Article and Find Full Text PDFThe present study illustrates the design, fabrication, and evaluation of a novel multifocal point (MFP) transducer based on polyvinylidene fluoride (PVDF) film for high-frequency ultrasound application. The fabricated MFP surface was press-focused using a computer numerical control (CNC) machining tool-customized multi-spherical pattern object. The multi-spherical pattern has five spherical surfaces with equal area and connected continuously to have the same energy level at focal points.
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