Publications by authors named "Thang Hong Pham"
Detection of Antiretroviral Drug-Resistant Mutations and HIV-1 Subtypes in Circulation Among Men Who Have Sex With Men, SEM Females, and Female Sex Workers: Results of Vietnam's HIV Sentinel Surveillance Plus System, 2018-2020.
J Acquir Immune Defic Syndr
January 2025
Article Synopsis
- HIV drug resistance (HIVDR) can decrease the effectiveness of antiretroviral drugs, and this study focused on assessing HIV-1 subtypes and drug resistance among key populations in Vietnam during 2018 and 2020.
- The study recruited participants from hotspots for men who have sex with men (MSM) and female sex workers (FSW) in various provinces, and 42.5% of HIV-positive samples had a viral load indicating the need for further testing for drug resistance.
- The results showed that CRF01_AE was the most common subtype, and 16.7% of participants had drug resistance mutations, with the majority being associated with NNRTI and NRTI classes, suggesting
Introduction: We assessed trends in HIV and syphilis prevalence, HIV incidence, related risk factors, and preventive behaviors among men who have sex with men (MSM) in Vietnam from 2015 to 2020.
Methods: Data originated from the HIV Sentinel Surveillance Plus system, which sampled MSM at venues and hotspots in seven of Vietnam's 63 provinces in 2015, 2016, 2018, and 2020 ( = 1100-1445 per year; ∼150-300 per province per year).
Results: HIV prevalence estimates increased from 6.
The Human Immunodeficiency Virus (HIV) epidemic remains a major public health issue worldwide. In Vietnam, the HIV epidemic is essentially driven by people who inject drugs (PWID). This study aims to compare mortality and loss to follow-up (LTFU) between PWID and other patients.
View Article and Find Full Text PDFArticle Synopsis
- Drug addiction is a chronic condition that requires long-term, community-based healthcare services to improve outcomes, yet there is limited research on effective sustainable interventions.
- This study aims to create and test an intervention that involves community health workers and family members to support individuals using drugs in Vietnam through integrated, individualized care.
- The intervention will be piloted across 60 randomized communities, evaluating outcomes related to drug users' fulfillment of treatment and the support provided by community workers and families over a year.
Introduction: Increasing access to viral load (VL) monitoring is essential to fight HIV epidemics. In remote settings in Vietnam, using dried blood spot (DBS) sampling for specimen collection could improve the situation. Here, people who inject drugs (PWID) represent many newly antiretroviral therapy (ART)-initiated patients.
View Article and Find Full Text PDFTo broaden access to HIV viral load monitoring (VLM), the use of blood samples from dried blood spots (DBS) or point-of-care (POC) devices, could be of great help in settings where plasma is not easily accessible. The variety of assays available makes the choice complex. This systematic review and meta-analysis aims to estimate the sensitivity and specificity of DBS and POC devices to identify patients in virological failure using World Health Organization (WHO) recommendations (viral load ≥1000 copies/mL), compared with plasma, for the assays currently available.
View Article and Find Full Text PDF