This study aimed to identify the recent risk factors for Opisthorchis viverrini infection and cholangiocarcinoma (CCA) to improve disease prevention. The participants were divided into the following 3 groups based on their health status: healthy control (nonOV and nonCCA), those with O. viverrini infection (OV), and those with CCA.
View Article and Find Full Text PDFIn Southeast Asian countries, nitrosamine compounds and the liver fluke have long been identified as carcinogens for cholangiocarcinoma (CHCA). In order to effectively treat infections and prevent the development of CHCA, methods for disease detection are needed. This study aims to identify biomarkers for infection and CHCA.
View Article and Find Full Text PDFParasitol Res
December 2022
Among the snail species acting as hosts for medically significant trematodes, only three taxa of Bithynia are responsible for transmitting the carcinogenic liver fluke Opisthorchis viverrini to humans in different geographical areas. Although B. siamensis goniomphalos is the primary species responsible for O.
View Article and Find Full Text PDFThe human liver fluke Opisthorchis viverrini (Ov), the primary risk factor for cholangiocarcinoma (CHCA), is a parasite endemic to southeast Asian countries. With no effective treatments for CHCA currently available, early diagnosis and treatment of Ov infection remains the only practical method for the prevention of CHCA. In this study, plasma phosphoproteomes of patients in the non-Ov infection, non-cholangiocarcinoma subject group (non-OVCCA), the asymptomatic Ov infected group (OV), and the CHCA group (CCA), were investigated to identify potential biomarkers for Ov infection and CHCA.
View Article and Find Full Text PDFBackground: Patients infected with a parasite often develop opisthorchiasis viverrini, which often progresses into cholangiocarcinoma (CCA) due to the asymptomatic nature of the infection. Currently, there are no effective diagnostic methods for opisthorchiasis or cholangiocarcinoma.
Objective: The aim of this study was to identify the host-responsive protein that can be developed as a diagnostic biomarker of opisthorchiasis and cholangiocarcinoma.
Cleft Palate Craniofac J
September 2020
Objective: To investigate the trend in cleft care at a major children's referral center in Bangkok, Thailand.
Study Design: Retrospective chart review.
Patients And Methods: A review of 129 patients under 18 years of age who had underwent care by the senior author for cleft treatment between January 2015 and October 2017 was done.
Opisthorchis viverrini infection, opisthorchiasis, is a food-borne trematodiasis that is the main cause of cholangiocarcinoma, a bile duct cancer, in the Lower Mekong sub-region of Lao PDR, Cambodia, Vietnam, and Thailand. Despite extensive research on opisthorchiasis, the eradication of this disease has yet to be achieved. One of the major reasons for this failure is due to the multi-host life cycle of the parasite, which requires complex medical and public health interventions to eradicate.
View Article and Find Full Text PDFObjective: To describe the current trend in balloon laryngoplasty usage and experience by practicing otolaryngologists in Thailand.
Study Design: Anonymous 11 question online and paper survey of otolaryngologists on their current balloon laryngoplasty practices.
Subjects And Methods: Current practices and experience in balloon laryngoplasty were queried with multiple choice and open-ended questions.