Publications by authors named "Thamyres Campos Fonseca"
A 41-year-old woman presented with a facial asymmetry in the mental region and a painful, well-circumscribed, tender mass in the right lower buccal vestibule, associated with extensive ill-defined bone rarefaction with subtle cortical bone resorption. Microscopically, a proliferation of bland spindle cells interspersed with collagen fibers and prominent staghorn-like blood vessels was observed. Immunohistochemical analysis revealed strong positivity for CD34, Bcl-2, CD99, and STAT-6, confirming the diagnosis of Solitary Fibrous Tumor (SFT).
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- The study analyzes the characteristics of oral reactions to injectable soft tissue fillers, focusing on 151 patients, predominantly females averaging 54.9 years old.
- Most reactions occurred about 20.4 months after injection, often presenting as painless nodules in the lips, with silicone and polymethylmetacrylate being the most common fillers used.
- Key findings showed differences in reaction patterns based on the type of filler and highlighted the importance for clinicians to recognize these potential reactions when assessing asymptomatic nodules in older female patients.
Objective: To conduct a systematic review to determine the global prevalence of HPV in oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma (OPSCC).
Materials And Methods: Literature was searched through October 2022 in main databases to address the question "What is the global prevalence of Human Papillomavirus in oral and oropharyngeal cancer?" Studies had to identify HPV by PCR, ISH, or p16 immunohistochemistry to be eligible. Quality was assessed using the JBI checklist for prevalence studies.
Background: This study aimed to investigate the clinicopathological features of metastases in the oral and maxillofacial regions.
Methods: In this retrospective study, biopsy records were obtained from referral centers for oral and maxillofacial diagnosis in Brazil, Guatemala, Mexico, and South Africa.
Results: A total of 120 cases were evaluated.
Article Synopsis
- The study aimed to investigate the frequency of oral squamous cell carcinoma (OSCC) in relation to oral potentially malignant disorders (OPMD) and understand the epidemiological profile in Latin America.
- A total of 2705 OSCC cases were analyzed, revealing a mean age of 62.8 years, with a higher prevalence among men, smokers, and drinkers, and the lateral tongue being the most affected area.
- The findings indicate that most cases were OSCC-de novo (81.4%), highlighting regional variations in OPMD, with leukoplakia being the most common, and suggest the need for additional studies to further explore this phenomenon.
Article Synopsis
- * The study involved clinical data from five patients, mostly middle-aged men, with issues primarily in the oral mucosa; all cases showed typical symptoms and characteristics of HPV-OED.
- * Patients received conservative surgical treatment, and after an average follow-up of 39 months, there were no signs of disease recurrence.
Low-Grade Myofibroblastic Sarcoma of the Oral and Maxillofacial Region: An International Clinicopathologic Study of 13 Cases and Literature Review.
Head Neck Pathol
September 2023
Article Synopsis
- Low-grade myofibroblastic sarcoma (LGMS) is a rare tumor typically found in the oral cavity and head/neck region, characterized by myofibroblast cells and a high chance of returning locally but low risk of spreading to distant sites.
- The study analyzed 13 cases of LGMS from various countries, revealing that most patients are young females, often presenting with nodular lesions in the maxilla, and exhibiting specific microscopic and immunohistochemical features that confirm the diagnosis.
- Complete surgical removal of the tumor is recommended for treatment, but additional long-term studies are needed to better understand recurrence rates and metastasis potential.
Background: Three years after the first confirmed COVID-19 case in Brazil, the outcomes of Federal government omissions in managing the crisis and anti-science stance heading into the pandemic have become even more evident. With over 36 million confirmed cases and nearly 700 000 deaths up to January 2023, the country is one of the hardest-hit places in the world. The lack of mass-testing programs was a critical broken pillar responsible for the quick and uncontrolled SARS-CoV-2 spread throughout the Brazilian population.
View Article and Find Full Text PDFTo compare two grading systems of epithelial dysplasia-World Health Organization (WHO) and binary system (BS) -in actinic cheilitis (AC). Seventy cases diagnosed as AC in an Oral Pathology Laboratory from Brazil in the last 12 years were retrospectively retrieved, including the demographic data of each patient. All conventionally stained slides were reviewed, and epithelial dysplasia was evaluated by two independent observers using both WHO and BS grading systems.
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