Publications by authors named "Thamer H Al-Khouzaie"

Article Synopsis
  • Mammalian target of rapamycin inhibitors (mTORi), like sirolimus and everolimus, are medications used for treating certain cancers and in organ transplant procedures.
  • Interstitial lung disease (ILD) is a potential complication associated with mTORi, with more cases linked to sirolimus compared to everolimus, possibly due to sirolimus being more widely used earlier on.
  • A specific case is presented where a kidney transplant patient developed ILD from sirolimus but showed quick improvement after switching to everolimus.
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A 45-year-old man presented with malaise, arthralgia, and dyspnea. The chest CT scan showed bilateral patchy consolidation in the lower lobes. A lung biopsy revealed intra-alveolar fibrin "balls" deposits and focal features of organizing pneumonia, both of which are typical pathological features of acute fibrinous and organizing pneumonia (AFOP).

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Objective: To assess the health-related quality of life (HRQL) of patients with chronic obstructive pulmonary disease (COPD) in 4 Gulf Council Cooperation (GCC) countries.

Methods: We conducted a cross-sectional survey between December 2011 and March 2012 in the following countries: Kingdom of Saudi Arabia (Riyadh, Dammam, and Jeddah), Kuwait, Bahrain, and the United Arab Emirates. The HRQL was measured using the COPD Assessment Test (CAT) and the Chronic Respiratory Disease Questionnaire-Self-Administered Standardized questionnaire (CRQ-SAS).

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Aim: To review a general hospital's experience with sarcoidosis and the clinical pattern of the disease among Saudis.

Methods: A retrospective file review was carried out on all patients with a proven diagnosis of sarcoidosis in a general hospital in Eastern Saudi Arabia over a period of 11 years (1998-2008).

Results: Sixty-nine patients, of whom 33 cases were included in the analyses, were diagnosed to have sarcoidosis during the study period.

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