The association of HLA-DQB1*0602 but not HLA-DRB1*15 with obstructive sleep apnea.

Purpose: Obstructive sleep apnea (OSA) is a sleep breathing disorder with unclear multifactorial pathogenesis. This study aimed to investigate the association between OSA and two human leukocyte antigens (HLA) alleles; DQB1*0602 and DRB1*15.

Methods: Forty patients with OSA and 40 control subjects were enrolled in the study.