Publications by authors named "Thalissa Colodiano Martins"
Validation of Lyophilized Human Fecal Microbiota for the Treatment of Infection: A Pilot Study with Pharmacoeconomic Analysis of a Middle-Income Country-Promicrobioma Project.
Carolina Hikari Yamada Gabriel Burato Ortis Gustavo Martini Buso Thalissa Colodiano Martins Tiago Zequinao
Microorganisms
August 2024
Article Synopsis
- CDI (Clostridioides difficile infection) is a serious health issue often caused by broad-spectrum antibiotics, prompting this study to analyze a new, lyophilized fecal microbiota transplant product for treating recurrent cases.
- A pilot study with 24 patients showed a 92% clinical response rate using the microbiota transplant, which was found to maintain significant bacterial viability.
- The cost-benefit analysis indicated that fecal microbiota transplantation is a safer and cheaper alternative to conventional treatments like vancomycin or metronidazole, potentially saving millions in healthcare costs in Brazil.